Anatol Manaenko, PhD

Contact Information

Department of Physiology
Loma Linda University
Loma Linda, CA 92350
Email: amanaenko@llu.edu

Research Interests

Cerebral Ischemia, hypoxia, purine nucleotide, stroke

Education

PhD 2002
Faculty of Bioscience, Pharmacy and Psychology of University of Leipzig, Germany

MSci 1987
Faculty of Natural Sciences, Novosibirsk State University, Russia

Training

2002 Post-Doctoral Fellow
Institute of Neurobiology, Magdeburg, Germany

2003-2004 Post-Doctoral Fellow
Institute of Human Genetic, University of Halle/Wittenberg, Halle/Saale, Germany

2004-2007 Post-Doctoral Fellow
Hospital and Health Centre for Neurology, University of Leipzig, Germany

2007- Post-Doctoral Fellow
Loma Linda University, Medical Center, Loma Linda, CA, USA

Awards

The Second Prize of the All-Union Student Scientific Conference, Novosibirsk, 1987.

The First Prize of the All-Union Student Scientific Conference, Novosibirsk, 1986.

Publications

Günther A, Manaenko A, Franke H, Wagner A, Schneider D,
Berrouschot J and Reinhardt R (2004). Hyperbaric and normobaric reoxygenation of hypoxic rat brain slices - impact on purine nucleotides and cell viability. Neurochem Int. 45: 1125-32.

Reinhardt R, Manaenko A, Guenther A, Franke H, Dickel T, Garcia de Arriba S, Muench G, Schneider D, Wagner A, Illes P. (2003) Early biochemical and histological alterations in rat corticoencephalic cell cultures following metabolic damage and treatment with modulators of mitochondrial ATP-sensitive potassium channels. Neurochem Int. 43(6): 563-571

Gunther A, Manaenko A, Franke H, Dickel T, Berrouschot J, Wagner A, Illes P, Reinhardt R. (2002) Early biochemical and histological changes during hyperbaric or normobaric reoxygenation after in vitro ischaemia in primary corticoencephalic cell cultures of rats. Brain Res. 946(1): 130-138

Reinhardt R, Manaenko A, Pissarek M, Wagner A, Illes P. (2002)
Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels. Neurochem Int. 427-433.

Pissarek M, Reinhardt R, Reichelt C, Manaenko A, Krauss G, Illes P.(1999). Rapid assay for one-run determination of purine and pyrimidine nucleotide contents in neocortical slices and cell cultures. Brain Res Protoc. 314-321.

Vtorushina I, Gorbunov I, Zarytova V, Komarova N, Lebedev A, Lochov S, Manaenko A, Siniakov A, Shishkina I. (1992). Diastereomers of nonionic oligonucleotide analogs. VI. Isolation of diastereomers of ethyl phosphotriesters of the octanucleotide d(GCCAAACA) by high performance affinity chromatography. Bioorg. Khim. 18: 92-99

Presentations

Manaenko A, Reinhardt R, Günter A, Berrouschot J, Wagner A and Illes P. (2002) Influence of oxygen pressure during the reoxygenation period on hypoxic induced decrease of purine and pyramidine nucleotide content in primary corticoencephalic cell cultures in wistar rats. 43. Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie, Mainz

Günther A, Reinhardt R, Manaenko A, Berrouschot J, Wagner A and Illes P. (2001) Purin- und Pyrimidingehalt in primären kortikoenzephalen Zellkulturen nach in vitro-Ischämie - Einfluss von hyperbarem Sauerstoff während der Reoxygenation. 74. Kongress Deutsche Gesellschaft für Neurologie, Aachen

Manaenko A, Reinardt R, Pissarek M, Wagner A and Illes P (2000) Tolbutamide a blocker of ATP-dependent potassium channels aggravate the hypoxic decrease of purine and pyrimidine nucleotide contents in primary corticoencephalic cell cultures.
1st International Workshop on Nucleotides and their Receptore in the Immune System; Ferrara, Italy

Günther A, Manaenko A, Franke H, Dickel T, Berrouschot J, Wagner A, Illes P and Reinhardt R. (2001) Influence of oxygen pressure during the reoxygenation period on hypoxic induced decrease of purine and pyramidine nucleotide content in primary corticoencephalic cell cultures in wistar rats.
Proceedings of the 4th Meeting of the German Neuroscience Society 2001; 28th Göttingen Neurobiology Conference; 892