Resources - Zhang Lab

Ostrowski RP, Zhang JH. The insights into molecular pathways of hypoxia-inducible factor in the brain. J Neurosci Res. 2020 Jan;98(1):57-76. doi: 10.1002/jnr.24366. Epub 2018 Dec 12. PMID: 30548473.

McBride DW, Gren ECK, Kelln W, Hayes WK, Zhang JH. Crotalus atrox disintegrin reduces hemorrhagic transformation by attenuating matrix metalloproteinase-9 activity after middle cerebral artery occlusion in hyperglycemic male rats. J Neurosci Res. 2020 Jan;98(1):191-200. doi: 10.1002/jnr.24334. Epub 2018 Sep 22. PMID: 30242872; PMCID: PMC6430696.

Lu T, Wang Z, Prativa S, Xu Y, Wang T, Zhang Y, Yu L, Xu N, Tang J, You W, Chen G, Zhang JH. Macrophage stimulating protein preserves blood brain barrier integrity after intracerebral hemorrhage through recepteur d'origine nantais dependent GAB1/Src/β-catenin pathway activation in a mouse model. J Neurochem. 2019 Jan;148(1):114-126. doi: 10.1111/jnc.14622. Epub 2018 Dec 5. PMID: 30380151; PMCID: PMC6333517.

Mo J, Enkhjargal B, Travis ZD, Zhou K, Wu P, Zhang G, Zhu Q, Zhang T, Peng J, Xu W, Ocak U, Chen Y, Tang J, Zhang J, Zhang JH. AVE 0991 attenuates oxidative stress and neuronal apoptosis via Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats. Redox Biol. 2019 Jan;20:75-86. doi: 10.1016/j.redox.2018.09.022. Epub 2018 Sep 28. PMID: 30296700; PMCID: PMC6174866.

Nowrangi DS, McBride D, Manaenko A, Dixon B, Tang J, Zhang JH. rhIGF-1 reduces the permeability of the blood-brain barrier following intracerebral hemorrhage in mice. Exp Neurol. 2019 Feb;312:72-81. doi: 10.1016/j.expneurol.2018.11.009. Epub 2018 Nov 30. PMID: 30503192.

Mo J, Huang L, Peng J, Ocak U, Zhang J, Zhang JH. Autonomic Disturbances in Acute Cerebrovascular Disease. Neurosci Bull. 2019 Feb;35(1):133-144. doi: 10.1007/s12264-018-0299-2. Epub 2018 Oct 11. PMID: 30311072; PMCID: PMC6357277.

Lu Z, Wang Z, Yu L, Ding Y, Xu Y, Xu N, Li R, Tang J, Chen G, Zhang JH. GCN2 reduces inflammation by p-eIF2α/ATF4 pathway after intracerebral hemorrhage in mice. Exp Neurol. 2019 Mar;313:16-25. doi: 10.1016/j.expneurol.2018.12.004. Epub 2018 Dec 6. PMID: 30529503.

Xie Z, Enkhjargal B, Wu L, Zhou K, Sun C, Hu X, Gospodarev V, Tang J, You C, Zhang JH. Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats. Neuropharmacology. 2018 Jan;128:142-151. doi: 10.1016/j.neuropharm.2017.09.040. Epub 2017 Oct 4. PMID: 28986282; PMCID: PMC5714662.

Zhou K, Enkhjargal B, Xie Z, Sun C, Wu L, Malaguit J, Chen S, Tang J, Zhang J, Zhang JH. Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat. Stroke. 2018 Jan;49(1):175-183. doi: 10.1161/STROKEAHA.117.018593. PMID: 29273596; PMCID: PMC5744882.

Wang T, Nowrangi D, Yu L, Lu T, Tang J, Han B, Ding Y, Fu F, Zhang JH. Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in intracerebral hemorrhage mice. J Neuroinflammation. 2018 Jan 4;15(1):2. doi: 10.1186/s12974-017-1039-7. PMID: 29301581; PMCID: PMC5753458.

Li Q, Ding Y, Krafft P, Wan W, Yan F, Wu G, Zhang Y, Zhan Q, Zhang JH. Targeting Germinal Matrix Hemorrhage-Induced Overexpression of Sodium-Coupled Bicarbonate Exchanger Reduces Posthemorrhagic Hydrocephalus Formation in Neonatal Rats. J Am Heart Assoc. 2018 Jan 31;7(3):e007192. doi: 10.1161/JAHA.117.007192. PMID: 29386206; PMCID: PMC5850237.

Lapchak PA, Zhang JH. Translational Stroke Research Guideline Projections: The 20/20 Standards. Transl Stroke Res. 2018 Feb;9(1):9-12. doi: 10.1007/s12975-017-0534-6. Epub 2017 Apr 6. PMID: 28386732.

Lapchak PA, Zhang JH. Data Standardization and Quality Management. Transl Stroke Res. 2018 Feb;9(1):4-8. doi: 10.1007/s12975-017-0531-9. Epub 2017 Mar 10. PMID: 28283966.

Zhang Y, Ding Y, Lu T, Zhang Y, Xu N, Yu L, McBride DW, Flores JJ, Tang J, Zhang JH. Bliverdin reductase-A improves neurological function in a germinal matrix hemorrhage rat model. Neurobiol Dis. 2018 Feb;110:122-132. doi: 10.1016/j.nbd.2017.11.017. Epub 2017 Dec 5. PMID: 29203281; PMCID: PMC5747982.

Wang Y, Sherchan P, Huang L, Akyol O, McBride DW, Zhang JH. Multiple mechanisms underlying neuroprotection by secretory phospholipase A2 preconditioning in a surgically induced brain injury rat model. Exp Neurol. 2018 Feb;300:30-40. doi: 10.1016/j.expneurol.2017.10.022. Epub 2017 Oct 24. PMID: 29074417; PMCID: PMC5745263.

Wu G, McBride DW, Zhang JH. Axl activation attenuates neuroinflammation by inhibiting the TLR/TRAF/NF-κB pathway after MCAO in rats. Neurobiol Dis. 2018 Feb;110:59-67. doi: 10.1016/j.nbd.2017.11.009. Epub 2017 Nov 28. PMID: 29196212; PMCID: PMC5748011.

McBride DW, Nowrangi D, Kaur H, Wu G, Huang L, Lekic T, Tang J, Zhang JH. A composite neurobehavioral test to evaluate acute functional deficits after cerebellar haemorrhage in rats. J Cereb Blood Flow Metab. 2018 Mar;38(3):433-446. doi: 10.1177/0271678X17696509. Epub 2017 Mar 20. PMID: 28318366; PMCID: PMC5851133.

Xie Z, Huang L, Enkhjargal B, Reis C, Wan W, Tang J, Cheng Y, Zhang JH. Recombinant Netrin-1 binding UNC5B receptor attenuates neuroinflammation and brain injury via PPARγ/NFκB signaling pathway after subarachnoid hemorrhage in rats. Brain Behav Immun. 2018 Mar;69:190-202. doi: 10.1016/j.bbi.2017.11.012. Epub 2017 Nov 21. PMID: 29162556; PMCID: PMC5894358.

McBride DW, Wu G, Nowrangi D, Flores JJ, Hui L, Krafft PR, Zhang JH. Delayed Recanalization Promotes Functional Recovery in Rats Following Permanent Middle Cerebral Artery Occlusion. Transl Stroke Res. 2018 Apr;9(2):185-198. doi: 10.1007/s12975-018-0610-6. Epub 2018 Jan 21. PMID: 29354887; PMCID: PMC6513323.

Chen S, Zhao L, Sherchan P, Ding Y, Yu J, Nowrangi D, Tang J, Xia Y, Zhang JH. Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice. J Neuroinflammation. 2018 Apr 11;15(1):106. doi: 10.1186/s12974-018-1140-6. PMID: 29642894; PMCID: PMC5896146.

Huang L, Boling W, Zhang JH. Hyperbaric oxygen therapy as adjunctive strategy in treatment of glioblastoma multiforme. Med Gas Res. 2018 Apr 18;8(1):24-28. doi: 10.4103/2045-9912.229600. PMID: 29770193; PMCID: PMC5937300.

Zhang Y, Ding Y, Lu T, Zhang Y, Xu N, McBride DW, Tang J, Zhang JH. Biliverdin reductase-A attenuated GMH-induced inflammatory response in the spleen by inhibiting toll-like receptor-4 through eNOS/NO pathway. J Neuroinflammation. 2018 Apr 20;15(1):118. doi: 10.1186/s12974-018-1155-z. PMID: 29678206; PMCID: PMC5910618.

Xu N, Zhang Y, Doycheva DM, Ding Y, Zhang Y, Tang J, Guo H, Zhang JH. Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats. Neuropharmacology. 2018 May 1;133:415-428. doi: 10.1016/j.neuropharm.2018.02.024. Epub 2018 Feb 24. PMID: 29486166.

Zhang Y, Xu N, Ding Y, Zhang Y, Li Q, Flores J, Haghighiabyaneh M, Doycheva D, Tang J, Zhang JH. Chemerin suppresses neuroinflammation and improves neurological recovery via CaMKK2/AMPK/Nrf2 pathway after germinal matrix hemorrhage in neonatal rats. Brain Behav Immun. 2018 May;70:179-193. doi: 10.1016/j.bbi.2018.02.015. Epub 2018 Mar 1. PMID: 29499303; PMCID: PMC5953818.

Zhu Q, Enkhjargal B, Huang L, Zhang T, Sun C, Xie Z, Wu P, Mo J, Tang J, Xie Z, Zhang JH. Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-κB pathway after subarachnoid hemorrhage in rats. J Neuroinflammation. 2018 Jun 9;15(1):178. doi: 10.1186/s12974-018-1211-8. PMID: 29885663; PMCID: PMC5994242.

Matei N, Camara J, McBride D, Camara R, Xu N, Tang J, Zhang JH. Intranasal wnt3a Attenuates Neuronal Apoptosis through Frz1/PIWIL1a/FOXM1 Pathway in MCAO Rats. J Neurosci. 2018 Jul 25;38(30):6787-6801. doi: 10.1523/JNEUROSCI.2352-17.2018. Epub 2018 Jun 28. PMID: 29954850; PMCID: PMC6067074.

Zhao L, Chen S, Sherchan P, Ding Y, Zhao W, Guo Z, Yu J, Tang J, Zhang JH. Recombinant CTRP9 administration attenuates neuroinflammation via activating adiponectin receptor 1 after intracerebral hemorrhage in mice. J Neuroinflammation. 2018 Jul 30;15(1):215. doi: 10.1186/s12974-018-1256-8. PMID: 30060752; PMCID: PMC6066941.

Gong L, Manaenko A, Fan R, Huang L, Enkhjargal B, McBride D, Ding Y, Tang J, Xiao X, Zhang JH. Osteopontin attenuates inflammation via JAK2/STAT1 pathway in hyperglycemic rats after intracerebral hemorrhage. Neuropharmacology. 2018 Aug;138:160-169. doi: 10.1016/j.neuropharm.2018.06.009. Epub 2018 Jun 7. PMID: 29885817; PMCID: PMC6487497.

Gamdzyk M, Doycheva DM, Malaguit J, Enkhjargal B, Tang J, Zhang JH. Role of PPAR-β/δ/miR-17/TXNIP pathway in neuronal apoptosis after neonatal hypoxic-ischemic injury in rats. Neuropharmacology. 2018 Sep 15;140:150-161. doi: 10.1016/j.neuropharm.2018.08.003. Epub 2018 Aug 4. PMID: 30086290; PMCID: PMC6223650.

Huang L, Applegate RL 2nd, Applegate PM, Boling W, Zhang JH. Inhalation of high concentration hydrogen gas improves short-term outcomes in a rat model of asphyxia induced-cardiac arrest. Med Gas Res. 2018 Sep 25;8(3):73-78. doi: 10.4103/2045-9912.241063. PMID: 30319760; PMCID: PMC6178639.

Akyol O, Sherchan P, Yilmaz G, Reis C, Ho WM, Wang Y, Huang L, Solaroglu I, Zhang JH. Neurotrophin-3 provides neuroprotection via TrkC receptor dependent pErk5 activation in a rat surgical brain injury model. Exp Neurol. 2018 Sep;307:82-89. doi: 10.1016/j.expneurol.2018.06.002. Epub 2018 Jun 5. PMID: 29883578; PMCID: PMC8893599.

Matei N, Camara R, Zhang JH. Emerging mechanisms and novel applications of hydrogen gas therapy. Med Gas Res. 2018 Sep 25;8(3):98-102. doi: 10.4103/2045-9912.239959. PMID: 30319764; PMCID: PMC6178641.

Li Q, Yang Y, Reis C, Tao T, Li W, Li X, Zhang JH. Cerebral Small Vessel Disease. Cell Transplant. 2018 Dec;27(12):1711-1722. doi: 10.1177/0963689718795148. Epub 2018 Sep 25. PMID: 30251566; PMCID: PMC6300773.

Yu J, Li X, Matei N, McBride D, Tang J, Yan M, Zhang JH. Ezetimibe, a NPC1L1 inhibitor, attenuates neuronal apoptosis through AMPK dependent autophagy activation after MCAO in rats. Exp Neurol. 2018 Sep;307:12-23. doi: 10.1016/j.expneurol.2018.05.022. Epub 2018 May 28. PMID: 29852178.

Wang F, Tang H, Zhu J, Zhang JH. Transplanting Mesenchymal Stem Cells for Treatment of Ischemic Stroke. Cell Transplant. 2018 Dec;27(12):1825-1834. doi: 10.1177/0963689718795424. Epub 2018 Sep 25. PMID: 30251564; PMCID: PMC6300770.

Klebe D, Iniaghe L, Burchell S, Reis C, Akyol O, Tang J, Zhang JH. Intracerebral Hemorrhage in Mice. Methods Mol Biol. 2018;1717:83-91. doi: 10.1007/978-1-4939-7526-6_7. PMID: 29468585.

S.L. Zuo, H.F. Ge, Q. Li, X. Zhang, R. Hu, S.L. Hu, X. Liu, J.H. Zhang, Y.J. Chen, H. Feng, Artesunate Protected Blood-Brain Barrier via Sphingosine 1 Phosphate Receptor 1/Phosphatidylinositol 3 Kinase Pathway After Subarachnoid Hemorrhage in Rats, Mol. Neurobiol., 54 (2017) 1213-1228.

S. Zhang, Y.X. Lai, X.F. Ding, M. Parsons, J.H. Zhang, M. Lou, Absent Filling of Ipsilateral Superficial Middle Cerebral Vein Is Associated With Poor Outcome After Reperfusion Therapy, Stroke, 48 (2017) 907-914.

Y. Yin, H.F. Ge, J.H. Zhang, H. Feng, Targeting Vascular Neural Network in Intracerebral Hemorrhage, Curr. Pharm. Design, 23 (2017) 2197-2205.

C. Yin, G.F. Huang, X.C. Sun, Z.D. Guo, J.H. Zhang, DLK silencing attenuated neuron apoptosis through JIP3/MA2K7/JNK pathway in early brain injury after SAH in rats, Neurobiol. Dis., 103 (2017) 133-143.

F. Yan, X.X. Tan, W.F. Wan, B.J. Dixon, R.M. Fan, B. Enkhjargal, Q. Li, J.M. Zhang, G. Chen, J.H. Zhang, ErbB4 protects against neuronal apoptosis via activation of YAP/PIK3CB signaling pathway in a rat model of subarachnoid hemorrhage, Exp. Neurol., 297 (2017) 92-100.

Z.Y. Xie, L. Huang, B. Enkhjargal, C. Reis, W.F. Wan, J.P. Tang, Y. Cheng, J.H. Zhang, Intranasal administration of recombinant Netrin-1 attenuates neuronal apoptosis by activating DCC/APPL-1/AKT signaling pathway after subarachnoid hemorrhage in rats, Neuropharmacology, 119 (2017) 123-133.

Z.Y. Xie, B. Enkhjargal, C. Reis, L. Huang, W.F. Wan, J.P. Tang, Y. Cheng, J.H. Zhang, Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats, J. Am. Heart Assoc., 6 (2017) 16.

P. Wu, Y.C. Li, S.Y. Zhu, C.L. Wang, J.X. Dai, G. Zhang, B.J. Zheng, S.C. Xu, L.G. Wang, T.Y. Zhang, P.Q. Zhou, J.H. Zhang, H.Z. Shi, Mdivi-1 Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats, Possibly via Inhibition of Drp1-Activated Mitochondrial Fission and Oxidative Stress, Neurochem. Res., 42 (2017) 1449-1458.

Y.C. Wang, P. Sherchan, L. Huang, O. Akyol, D.W. McBride, J.H. Zhang, Naja sputatrix Venom Preconditioning Attenuates Neuroinflammation in a Rat Model of Surgical Brain Injury via PLA2/5LOX/LTB4 Cascade Activation, Scientific Reports, 7 (2017) 12.

G.Q. Wang, A. Manaenko, A.W. Shao, Y.B. Ou, P. Yang, E. Budbazar, D. Nowrangi, J.H. Zhang, J.P. Tang, Low-density lipoprotein receptor-related protein-1 facilitates heme scavenging after intracerebral hemorrhage in mice, J. Cereb. Blood Flow Metab., 37 (2017) 1299-1310.

L.S. Tong, A.W. Shao, Y.B. Ou, Z.N. Guo, A. Manaenko, B.J. Dixon, J.P. Tang, M. Lou, J.H. Zhang, Recombinant Gas6 augments Axl and facilitates immune restoration in an intracerebral hemorrhage mouse model, J. Cereb. Blood Flow Metab., 37 (2017) 1971-1981.

X.D. Shi, L. Xu, J. Malagult, J.P. Tang, M. Yan, J.H. Zhang, Sestrins: A New Kid for Stroke Treatment?, Curr. Drug Deliv., 14 (2017) 797-806.

X.D. Shi, L. Xu, D.M. Doycheva, J.P. Tang, M. Yan, J.H. Zhang, Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups, J. Cereb. Blood Flow Metab., 37 (2017) 1447-1460.

P. Sherchan, L. Huang, O. Akyol, C. Reis, J.P. Tang, J.H. Zhang, Recombinant Slit2 Reduces Surgical Brain Injury Induced Blood Brain Barrier Disruption via Robo4 Dependent Rac1 Activation in a Rodent Model, Scientific Reports, 7 (2017) 11.

A. Salehi, J.H. Zhang, A. Obenaus, Response of the cerebral vasculature following traumatic brain injury, J. Cereb. Blood Flow Metab., 37 (2017) 2320-2339.

W.B. Rolland, P.R. Krafft, T. Lekic, D. Klebe, J. LeGrand, A.J. Weldon, L. Xu, J.H. Zhang, Fingolimod confers neuroprotection through activation of Rac1 after experimental germinal matrix hemorrhage in rat pups, J. Neurochem., 140 (2017) 776-786.

C. Reis, M. Wilkinson, H. Reis, O. Akyol, V. Gospodarev, C. Araujo, S. Chen, J.H. Zhang, A Look into Stem Cell Therapy: Exploring the Options for Treatment of Ischemic Stroke, Stem Cells Int., (2017) 14.

C. Reis, V. Gospodarev, H. Reis, M. Wilkinson, J. Gaio, C. Araujo, S. Chen, J.H. Zhang, Traumatic Brain Injury and Stem Cell: Pathophysiology and Update on Recent Treatment Modalities, Stem Cells Int., (2017) 13.

C. Reis, O. Akyol, W.M. Ho, C. Araujo, L. Huang, R. Applegate, J.H. Zhang, Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research, Biomed Res. Int., (2017) 14.

C. Reis, O. Akyol, C. Araujo, L. Huang, B. Enkhjargal, J. Malaguit, V. Gospodarev, J.H. Zhang, Pathophysiology and the Monitoring Methods for Cardiac Arrest Associated Brain Injury, Int. J. Mol. Sci., 18 (2017) 18.

P.Y. Pan, X. Zhang, Q. Li, H.L. Zhao, J. Qu, J.H. Zhang, X. Liu, H. Feng, Y.J. Chen, Cyclosporine A alleviated matrix metalloproteinase 9 associated blood-brain barrier disruption after subarachnoid hemorrhage in mice, Neurosci. Lett., 649 (2017) 7-13.

A. Obenaus, M. Ng, A.M. Orantes, E. Kinney-Lang, F. Rashid, M. Hamer, R.A. DeFazio, J. Tang, J.H. Zhang, W.J. Pearce, Traumatic brain injury results in acute rarefication of the vascular network, Scientific Reports, 7 (2017) 14.

A. Obenaus, M. Ng, A. Orantes, E. Kinney-Lang, F. Rashid, M. Hamer, R. DeFazio, J.P. Tang, J.H. Zhang, W.J. Pearce, Traumatic brain injury results in acute rarefication of the vascular network, J. Neurotrauma, 34 (2017) A80-A81.

D.W. McBride, J.H. Zhang, Precision Stroke Animal Models: the Permanent MCAO Model Should Be the Primary Model, Not Transient MCAO, Transl. Stroke Res., 8 (2017) 397-404.

D.W. McBride, S.L. Blackburn, T.P. Kumar, K. Matsumura, J.H. Zhang, The Role of Thromboinflammation in Delayed Cerebral ischemia after Subarachnoid Hemorrhage, Front. Neurol., 8 (2017) 9.

D. McBride, J.P. Tang, J.H. Zhang, Maintaining Plasma Fibrinogen Levels and Fibrinogen Replacement Therapies for Treatment of Intracranial Hemorrhage, Curr. Drug Targets, 18 (2017) 1349-1357.

L. Ma, A. Manaenko, Y.B. Ou, A.W. Shao, S.X. Yang, J.H. Zhang, Bosutinib Attenuates Inflammation via Inhibiting Salt-Inducible Kinases in Experimental Model of Intracerebral Hemorrhage on Mice, Stroke, 48 (2017) 3108-+.

C.L. Lin, A.S. Dumont, J.H. Zhang, M. Zuccarello, C.S. Chen, Improving and Predicting Outcomes of Traumatic Brain Injury: Neuroplasticity, Imaging Modalities, and Perspective Therapy, Neural. Plast., (2017) 2.

T. Lekic, D. Klebe, P. Pichon, K. Brankov, S. Sultan, D. McBride, D. Casel, A. Al-Bayati, Y. Ding, J.P. Tang, J.H. Zhang, Aligning Animal Models of Clinical Germinal Matrix Hemorrhage, From Basic Correlation to Therapeutic Approach, Curr. Drug Targets, 18 (2017) 1316-1328.

P.A. Lapchak, J.H. Zhang, The High Cost of Stroke and Stroke Cytoprotection Research, Transl. Stroke Res., 8 (2017) 307-317.

Y.J. Lai, D. Yu, J.H. Zhang, G.J. Chen, Cooperation of Genomic and Rapid Nongenomic Actions of Estrogens in Synaptic Plasticity, Mol. Neurobiol., 54 (2017) 4113-4126.

P.R. Krafft, D. McBride, W.B. Rolland, T. Lekic, J.J. Flores, J.H. Zhang, alpha 7 Nicotinic Acetylcholine Receptor Stimulation Attenuates Neuroinflammation through JAK2-STAT3 Activation in Murine Models of Intracerebral Hemorrhage, Biomed Res. Int., (2017) 13.

D. Klebe, J.J. Flores, D.W. McBride, P.R. Krafft, W.B. Rolland, T. Lekic, J.H. Zhang, Dabigatran ameliorates post-haemorrhagic hydrocephalus development after germinal matrix haemorrhage in neonatal rat pups, J. Cereb. Blood Flow Metab., 37 (2017) 3135-3149.

C.H. Kim, D.W. McBride, P. Sherchan, C.E. Person, E.C.K. Gren, W. Kelln, T. Lekic, W.K. Hayes, J.P. Tang, J.H. Zhang, Crotalus helleri venom preconditioning reduces postoperative cerebral edema and improves neurological outcomes after surgical brain injury, Neurobiol. Dis., 107 (2017) 66-72.

C.H. Kim, D.W. McBride, R. Raval, P. Sherchan, K.L. Hay, E.C.K. Gren, W. Kelln, T. Lekic, W.K. Hayes, B.S. Bull, R. Applegate, J.P. Tang, J.H. Zhang, Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury, Scientific Reports, 7 (2017) 11.

Q. Hu, A. Manaenko, H.T. Bian, Z.D. Guo, J.L. Huang, Z.N. Guo, P. Yang, J.P. Tang, J.H. Zhang, Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD(+)/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats, Stroke, 48 (2017) 1655-+.

L.T. Hu, B.L. Zhu, Y.J. Lai, Y. Long, J.S. Zha, X.T. Hu, J.H. Zhang, G.J. Chen, HMGCS2 promotes autophagic degradation of the amyloid-beta precursor protein through ketone body-mediated mechanisms, Biochem. Biophys. Res. Commun., 486 (2017) 492-498.

W.M. Ho, C. Reis, O. Akyol, G.Y. Akyol, R. Applegate, G. Stier, R. Martin, J.H. Zhang, Pharmacological Management Options to Prevent and Reduce Ischemic Hemorrhagic Transformation, Curr. Drug Targets, 18 (2017) 1441-1459.

Y. Hasegawa, K. Duris, L.Y. Miao, N. Shimamura, J.H. Zhang, Targeting Cerebral Vascular Injury for Intervention, Curr. Drug Deliv., 14 (2017) 742-743.

R.M. Fan, B. Enkhjargal, R. Camara, F. Yan, L. Gong, ShengtaoYao, J.P. Tang, Y.M. Chen, J.H. Zhang, Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat, Exp. Neurol., 296 (2017) 41-48.

B. Enkhjargal, D.W. McBride, A. Manaenko, C. Reis, Y. Sakai, J.P. Tang, J.H. Zhang, Intranasal administration of vitamin D attenuates blood-brain barrier disruption through endogenous upregulation of osteopontin and activation of CD44/P-gp glycosylation signaling after subarachnoid hemorrhage in rats, J. Cereb. Blood Flow Metab., 37 (2017) 2555-2566.

G. Chen, P. Lackner, I. Solaroglu, J.H. Zhang, Brain Hemorrhages and Future Management, Curr. Drug Targets, 18 (2017) 1315-1315.

S.R. Burchell, J.P. Tang, J.H. Zhang, Hematoma Expansion Following Intracerebral Hemorrhage: Mechanisms Targeting the Coagulation Cascade and Platelet Activation, Curr. Drug Targets, 18 (2017) 1329-1344.

S.R. Burchell, L. Iniaghe, C. Reis, S. Aka, K. Hay, R. Raval, J.H. Zhang, J.P. Tang, Activation of Platelet CLEC-2 in Hematoma Expansion After Intracerebral Hemorrhage: Finding an Effective Dose, Arterioscler. Thromb. Vasc. Biol., 37 (2017) 1.

F. Bosetti, J.I. Koenig, C. Ayata, S.A. Back, K. Becker, J.P. Broderick, S.T. Carmichael, S. Cho, M.J. Cipolla, D. Corbett, R.A. Corriveau, S.C. Cramer, A.R. Ferguson, S.P. Finklestein, B.D. Ford, K.L. Furie, T.M. Hemmen, C. Iadecola, L.B. Jakeman, S. Janis, E.C. Jauch, K.C. Johnston, P.M. Kochanek, H. Kohn, E.H. Lo, P.D. Lyden, C. Mallard, L.D. McCullough, L.M. McGavern, J.F. Meschia, C.S. Moy, M.A. Perez-Pinzon, I. Ramadan, S.I. Savitz, L.H. Schwamm, G.K. Steinberg, M.P. Stenzel-Poore, M. Tymianski, S. Warach, L.R. Wechsler, J.H. Zhang, W. Koroshetz, Translational Stroke Research Vision and Opportunities, Stroke, 48 (2017) 2632-2637.

H.L. Zhao, X. Zhang, Z.Q. Dai, Y. Feng, Q. Li, J.H. Zhang, X. Liu, Y.J. Chen, H. Feng, P2X7 Receptor Suppression Preserves Blood-Brain Barrier through Inhibiting RhoA Activation after Experimental Intracerebral Hemorrhage in Rats, Scientific Reports, 6 (2016) 14.

J.H. Zhang, Precision Translational Stroke Research, Cell Transplant., 25 (2016) 778-778.

C. Yin, G.F. Huang, X.C. Sun, Z.D. Guo, J.H. Zhang, Tozasertib attenuates neuronal apoptosis via DLK/JIP3/MA2K7/JNK pathway in early brain injury after SAH in rats, Neuropharmacology, 108 (2016) 316-323.

P. Yang, J. Wu, L.Y. Miao, A. Manaenko, N. Matei, Y. Zhang, L. Xu, W.J. Pearce, R.E. Hartman, A. Obenaus, J.H. Zhang, F. Xu, J.P. Tang, Platelet-Derived Growth Factor Receptor-beta Regulates Vascular Smooth Muscle Cell Phenotypic Transformation and Neuroinflammation After Intracerebral Hemorrhage in Mice, Crit. Care Med., 44 (2016) E390-E402.

P. Yang, A. Manaenko, F. Xu, L.Y. Miao, G.Q. Wang, X.Z. Hu, Z.N. Guo, Q. Hu, R.E. Hartman, W.J. Pearce, A. Obenaus, J.H. Zhang, G. Chen, J.P. Tang, Role of PDGF-D and PDGFR-beta in neuroinflammation in experimental ICH mice model, Exp. Neurol., 283 (2016) 157-164.

H. Yan, Y.J. Chen, L.Y. Li, J.D. Jiang, G.Y. Wu, Y.C. Zuo, J.H. Zhang, H. Feng, X.X. Yan, F. Liu, Decorin alleviated chronic hydrocephalus via inhibiting TGF-beta 1/Smad/CTGF pathway after subarachnoid hemorrhage in rats, Brain Res., 1630 (2016) 241-253.

J. Wu, Y. Zhang, P. Yang, B. Enkhjargal, A. Manaenko, J.P. Tang, W.J. Pearce, R. Hartman, A. Obenaus, G. Chen, J.H. Zhang, Recombinant Osteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/Integrin-Linked Kinase/Rac-1 Pathway After Subarachnoid Hemorrhage in Rats, Stroke, 47 (2016) 1319-1327.

X.D. Shi, D.M. Doycheva, L. Xu, J.P. Tang, M. Yan, J.H. Zhang, Sestrin2 induced by hypoxia inducible factor1 alpha protects the blood-brain barrier via inhibiting VEGF after severe hypoxic-ischemic injury in neonatal rats, Neurobiol. Dis., 95 (2016) 111-121.

P. Sherchan, L. Huang, Y.C. Wang, O. Akyol, J.P. Tang, J.H. Zhang, Recombinant Slit2 attenuates neuroinflammation after surgical brain injury by inhibiting peripheral immune cell infiltration via Robo1-srGAP1 pathway in a rat model, Neurobiol. Dis., 85 (2016) 164-173.

W.J. Pearce, C. Doan, D. Carreon, D. Kim, L.M. Durrant, A. Manaenko, L. McCoy, A. Obenaus, J.H. Zhang, J.P. Tang, Imatinib attenuates cerebrovascular injury and phenotypic transformation after intracerebral hemorrhage in rats, Am. J. Physiol.-Regul. Integr. Comp. Physiol., 311 (2016) R1093-R1104.

D.W. McBride, C. Reis, E. Frank, D.W. Klebe, J.H. Zhang, R. Applegate, J.P. Tang, An Experimental Model of Vasovagal Syncope Induces Cerebral Hypoperfusion and Fainting-Like Behavior in Awake Rats, Plos One, 11 (2016) 14.

Z. Liu, Q. Li, G.Y. Cui, G. Zhu, W.H. Tang, H.L. Zhao, J.H. Zhang, Y.J. Chen, H. Feng, Blood-filled cerebrospinal fluid-enhanced pericyte microvasculature contraction in rat retina: A novel in vitro study of subarachnoid hemorrhage, Exp. Ther. Med., 12 (2016) 2411-2416.

F. Liao, G.F. Li, W. Yuan, Y.J. Chen, Y.C. Zuo, K. Rashid, J.H. Zhang, H. Feng, F. Liu, LSKL peptide alleviates subarachnoid fibrosis and hydrocephalus by inhibiting TSP1-mediated TGF-beta 1 signaling activity following subarachnoid hemorrhage in rats, Exp. Ther. Med., 12 (2016) 2537-2543.

Q. Li, Y.J. Chen, X. Zhang, S.L. Zuo, H.F. Ge, Y.Y. Chen, X. Liu, J.H. Zhang, H.Z. Ruan, H. Feng, Scutellarin attenuates vas ospasm through the Erk5-KLF2-eNOS pathway after subarachnoid hemorrhage in rats, J. Clin. Neurosci., 34 (2016) 264-270.

Q. Li, Y.J. Chen, B. Li, C.X. Luo, S.L. Zuo, X. Liu, J.H. Zhang, H.Z. Ruan, H. Feng, Hemoglobin induced NO/cGMP suppression Deteriorate Microcirculation via Pericyte Phenotype Transformation after Subarachnoid Hemorrhage in Rats, Scientific Reports, 6 (2016) 14.

D. Kim, C. Doan, D. Carreon, E. Budbazar, J.H. Zhang, W.J. Pearce, Osteopontin Attenuates Changes in Cerebrovascular Structure-Function Relations Induced by Subarachnoid Hemorrhage in Rat Brain, Faseb J., 30 (2016) 1.

L.O. Iniaghe, S.R. Burchell, J.H. Zhang, J.P. Tang, Activation of the Cannabinoid Receptor 2 by JWH133 attenuates neurological deficits and brain edema after experimental intracerebral hemorrhage in mice, Faseb J., 30 (2016) 2.

L. Huang, A. Obenaus, M. Hamer, J.H. Zhang, Neuroprotective effect of hyperbaric oxygen therapy in a juvenile rat model of repetitive mild traumatic brain injury, Med. Gas Res., 6 (2016) 187-193.

Q. Hu, A. Manaenko, T. Xu, Z.N. Guo, J.P. Tang, J.H. Zhang, Hyperbaric oxygen therapy for traumatic brain injury: bench-to-bedside, Med. Gas Res., 6 (2016) 102-110.

Q. Hu, A. Manaenko, N. Matei, Z.N. Guo, T. Xu, J.P. Tang, J.H. Zhang, Hyperbaric oxygen preconditioning: a reliable option for neuroprotection, Med. Gas Res., 6 (2016) 20-32.

Z.N. Guo, L. Xu, Q. Hu, N. Matei, P. Yang, L.S. Tong, Y. He, Z.D. Guo, J.P. Tang, Y. Yang, J.H. Zhang, Hyperbaric Oxygen Preconditioning Attenuates Hemorrhagic Transformation Through Reactive Oxygen Species/Thioredoxin-Interacting Protein/Nod-Like Receptor Protein 3 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats, Crit. Care Med., 44 (2016) E403-E411.

Z.D. Guo, Q. Hu, L. Xu, Z.N. Guo, Y.B. Ou, Y. He, C. Yin, X.C. Sun, J.P. Tang, J.H. Zhang, Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats, Stroke, 47 (2016) 490-+.

J.J. Flores, D. Klebe, W.B. Rolland, T. Lekic, P.R. Krafft, J.H. Zhang, PPAR gamma-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats, Neurobiol. Dis., 87 (2016) 124-133.

B.J. Dixon, J.H. Zhang, Hydrogen Molecular Biology and Medicine, Med. Gas Res., 6 (2016) 55-56.

B.J. Dixon, J.H. Zhang, New Beginnings for Medical Gas Research, Med. Gas Res., 6 (2016) 1-2.

B.J. Dixon, D. Chen, Y. Zhang, J. Flores, J. Malaguit, D. Nowrangi, J.H. Zhang, J.P. Tang, Intranasal Administration of Interferon Beta Attenuates Neuronal Apoptosis via the JAK1/STAT3/BCL-2 Pathway in a Rat Model of Neonatal Hypoxic-Ischemic Encephalopathy, Asn Neuro, 8 (2016) 14.

R. Camara, L. Huang, J.H. Zhang, The production of high dose hydrogen gas by the AMS-H-01 for treatment of disease, Med. Gas Res., 6 (2016) 164-166.

A. Bahrami, S. Lee, G. Wu, J. Kerstetter, M. Rahvar, X.M. Li, J. Easton, J.H. Zhang, R.L. Barnhill, Pigment-Synthesizing Melanocytic Neoplasm With Protein Kinase C Alpha (PRKCA) Fusion, JAMA Dermatol., 152 (2016) 318-322.

S.L. Zuo, W.Y. Li, Q. Li, H.L. Zhao, J. Tang, Q.W. Chen, X. Liu, J.H. Zhang, Y.J. Chen, H. Feng, Protective effects of Ephedra sinica extract on blood-brain barrier integrity and neurological function correlate with complement C3 reduction after subarachnoid hemorrhage in rats, Neurosci. Lett., 609 (2015) 216-222.

Y. Zheng, Q. Hu, A. Manaenko, Y. Zhang, Y. Peng, L. Xu, J.J. Tang, J.P. Tang, J.H. Zhang, 17 beta-Estradiol Attenuates Hematoma Expansion Through Estrogen Receptor alpha/Silent Information Regulator 1/Nuclear Factor-kappa B Pathway in Hyperglycemic Intracerebral Hemorrhage Mice, Stroke, 46 (2015) 485-491.

Y. Zhang, Y.J. Chen, J. Wu, A. Manaenko, P. Yang, J.P. Tang, W.L. Fu, J.H. Zhang, Activation of Dopamine D2 Receptor Suppresses Neuroinflammation Through alpha B-Crystalline by Inhibition of NF-kappa B Nuclear Translocation in Experimental ICH Mice Model, Stroke, 46 (2015) 2637-2646.

Y. Zhan, P.R. Krafft, T. Lekic, Q.Y. Ma, R. Souvenir, J.H. Zhang, J.P. Tang, Imatinib Preserves Blood-Brain Barrier Integrity Following Experimental Subarachnoid Hemorrhage in Rats, J. Neurosci. Res., 93 (2015) 94-103.

F. Yang, Z. Wang, J.H. Zhang, J.P. Tang, X. Liu, L. Tan, Q.Y. Huang, H. Feng, Receptor for Advanced Glycation End-Product Antagonist Reduces Blood-Brain Barrier Damage After Intracerebral Hemorrhage, Stroke, 46 (2015) 1328-1336.

L. Xu, Z.N. Guo, Y. Yang, J. Xu, S.R. Burchell, J.P. Tang, J.M. Zhang, J. Xu, J.H. Zhang, Angiopoietin-like 4: A double-edged sword in atherosclerosis and ischemic stroke?, Exp. Neurol., 272 (2015) 61-66.

Y.C. Wang, C. Reis, R. Applegate, G. Stier, R. Martin, J.H. Zhang, Ischemic conditioning-induced endogenous brain protection: Applications pre-, per- or post-stroke, Exp. Neurol., 272 (2015) 26-40.

J.J. Tang, Q. Hu, Y.J. Chen, F. Liu, Y. Zheng, J.P. Tang, J.M. Zhang, J.H. Zhang, Neuroprotective role of an N-acetyl serotonin derivative via activation of tropomyosin-related kinase receptor B after subarachnoid hemorrhage in a rat model, Neurobiol. Dis., 78 (2015) 126-133.

L. Tan, B. Margaret, J.H. Zhang, R. Hu, Y. Yin, L. Cao, H. Feng, Y.Q. Zhang, Efficacy and Safety of Cilostazol Therapy in Ischemic Stroke: A Meta-analysis, J. Stroke Cerebrovasc. Dis., 24 (2015) 930-938.

R. Souvenir, D. Doycheva, J.H. Zhang, J.P. Tang, Erythropoietin in Stroke Therapy: Friend or Foe, Curr. Med. Chem., 22 (2015) 1205-1213.

I. Solaroglu, M. Digicaylioglu, G.E. Keles, J.H. Zhang, New Missions for an Old Agent: Granulocyte-Colony Stimulating Factor in the Treatment of Stroke Patients, Curr. Med. Chem., 22 (2015) 1302-1309.

C. Reis, Y.C. Wang, O. Akyol, W.M. Ho, R. Applegate, G. Stier, R. Martin, J.H. Zhang, What's New in Traumatic Brain Injury: Update on Tracking, Monitoring and Treatment, Int. J. Mol. Sci., 16 (2015) 11903-11965.

D.W. McBride, Y.C. Wang, P. Sherchan, J.P. Tang, J.H. Zhang, Correlation between subacute sensorimotor deficits and brain water content after surgical brain injury in rats, Behav. Brain Res., 290 (2015) 161-171.

D.W. McBride, D. Klebe, J.P. Tang, J.H. Zhang, Correcting for Brain Swelling's Effects on Infarct Volume Calculation After Middle Cerebral Artery Occlusion in Rats, Transl. Stroke Res., 6 (2015) 323-338.

F. Liu, Y.J. Chen, Q. Hu, B. Li, J.J. Tang, Y. He, Z.D. Guo, H. Feng, J.P. Tang, J.H. Zhang, MFGE8/Integrin beta 3 pathway alleviates apoptosis and inflammation in early brain injury after subarachnoid hemorrhage in rats, Exp. Neurol., 272 (2015) 120-127.

L. Li, D.W. McBride, D. Doycheva, B.J. Dixon, P.R. Krafft, J.H. Zhang, J.P. Tang, G-CSF attenuates neuroinflammation and stabilizes the blood-brain barrier via the PI3K/Akt/GSK-3 beta signaling pathway following neonatal hypoxia-ischemia in rats, Exp. Neurol., 272 (2015) 135-144.

L. Li, D. Klebe, D. Doycheva, D.W. McBride, P.R. Krafft, J. Flores, C.M. Zhou, J.H. Zhang, J.P. Tang, G-CSF ameliorates neuronal apoptosis through GSK-3 beta inhibition in neonatal hypoxia-ischemia in rats, Exp. Neurol., 263 (2015) 141-149.

B. Li, Y. He, L. Xu, Q. Hu, J.J. Tang, Y.J. Chen, J.P. Tang, H. Feng, J.H. Zhang, Progranulin Reduced Neuronal Cell Death by Activation of Sortilin 1 Signaling Pathways After Subarachnoid Hemorrhage in Rats, Crit. Care Med., 43 (2015) E304-E311.

T. Lekic, D. Klebe, R. Poblete, P.R. Krafft, W.B. Rolland, J.P. Tang, J.H. Zhang, Neonatal Brain Hemorrhage (NBH) of Prematurity: Translational Mechanisms of the Vascular-Neural Network, Curr. Med. Chem., 22 (2015) 1214-1238.

T. Lekic, D. Klebe, D.W. McBride, A. Manaenko, W.B. Rolland, J.J. Flores, O. Altay, J.P. Tang, J.H. Zhang, Protease-Activated Receptor 1 and 4 Signal Inhibition Reduces Preterm Neonatal Hemorrhagic Brain Injury, Stroke, 46 (2015) 1710-+.

D. Klebe, D. McBride, J.J. Flores, J.H. Zhang, J.P. Tang, Modulating the Immune Response Towards a Neuroregenerative Peri-injury Milieu After Cerebral Hemorrhage, J. Neuroimmune Pharm., 10 (2015) 576-586.

L.O. Iniaghe, P.R. Krafft, D.W. Klebe, E.K.I. Omogbai, J.H. Zhang, J.P. Tang, Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage, Neurobiol. Dis., 82 (2015) 349-358.

L. Huang, P. Sherchan, Y.C. Wang, C. Reis, R.L. Applegate, J.P. Tang, J.H. Zhang, Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury, J. Neurosci., 35 (2015) 10390-10401.

Q. Hu, A. Manaenko, Z.N. Guo, L. Huang, J.P. Tang, J.H. Zhang, Hyperbaric oxygen therapy for post concussion symptoms: issues may affect the results, Med. Gas Res., 5 (2015) 3.

Y. He, L. Xu, B. Li, Z.N. Guo, Q. Hu, Z.D. Guo, J.J. Tang, Y.J. Chen, Y. Zhang, J.P. Tang, J.H. Zhang, Macrophage-Inducible C-Type Lectin/Spleen Tyrosine Kinase Signaling Pathway Contributes to Neuroinflammation After Subarachnoid Hemorrhage in Rats, Stroke, 46 (2015) 2277-2286.

B.J. Dixon, C. Reis, W.M. Ho, J.P. Tang, J.H. Zhang, Neuroprotective Strategies after Neonatal Hypoxic Ischemic Encephalopathy, Int. J. Mol. Sci., 16 (2015) 22368-22401.

Y.J. Chen, Y. Zhang, J.J. Tang, F. Liu, Q. Hu, C.X. Luo, J.P. Tang, H. Feng, J.H. Zhang, Norrin Protected Blood-Brain Barrier Via Frizzled-4/beta-Catenin Pathway After Subarachnoid Hemorrhage in Rats, Stroke, 46 (2015) 529-536.

Y.J. Chen, C.X. Luo, M.Y. Zhao, Q. Li, R. Hu, J.H. Zhang, Z. Liu, H. Feng, Administration of a PTEN inhibitor BPV(pic) attenuates early brain injury via modulating AMPA receptor subunits after subarachnoid hemorrhage in rats, Neurosci. Lett., 588 (2015) 131-136.

Y.J. Chen, Q. Li, J.P. Tang, H. Feng, J.H. Zhang, The evolving roles of pericyte in early brain injury after subarachnoid hemorrhage, Brain Res., 1623 (2015) 110-122.

Y.J. Chen, H. Feng, J.H. Zhang, Response to Letter Regarding Article, "Norrin Protected Blood-Brain Barrier via Frizzled-4/beta-Catenin Pathway After Subarachnoid Hemorrhage in Rats", Stroke, 46 (2015) E91-E91.

S. Chen, Q.W. Yang, G. Chen, J.H. Zhang, An Update on Inflammation in the Acute Phase of Intracerebral Hemorrhage, Transl. Stroke Res., 6 (2015) 4-8.

S. Chen, Y.J. Chen, L. Xu, N. Matei, J.P. Tang, H. Feng, J.H. Zhang, Venous system in acute brain injury: Mechanisms of pathophysiological change and function, Exp. Neurol., 272 (2015) 4-10.

Q.W. Chen, J. Tang, L. Tan, J. Guo, Y.H. Tao, L. Li, Y.J. Chen, X. Liu, J.H. Zhang, Z. Chen, H. Feng, Intracerebral Hematoma Contributes to Hydrocephalus After Intraventricular Hemorrhage via Aggravating Iron Accumulation, Stroke, 46 (2015) 2902-2908.

H.T. Bian, Q. Hu, X.P. Liang, D. Chen, B. Li, J.P. Tang, J.H. Zhang, Hyperbaric oxygen preconditioning attenuates hemorrhagic transformation through increasing PPAR gamma in hyperglycemic MCAO rats, Exp. Neurol., 265 (2015) 22-29.

McBride DW, Wang Y, Sherchan P, Tang J, Zhang JH. Correlation between sub-acute sensorimotor deficits and brain water content after surgical brain injury in rats. Behav Brain Res. 2015 Sep 1;290:161-71.

Tang J, Hu Q, Chen Y, Liu F, Zheng Y, Tang J, Zhang J, Zhang JH. Neuroprotective role of an N-acetyl serotonin derivative via activation of tropomyosin-related kinase receptor B after subarachnoid hemorrhage in a rat model. Neurobiol Dis. 2015 Jun;78:126-33.

Lekic T, Klebe D, McBride DW, Manaenko A, Rolland WB, Flores JJ, Altay O, Tang J, Zhang JH. Protease-activated receptor 1 and 4 signal inhibition reduces pre-term neonatal hemorrhagic brain injury. Stroke. 2015 Jun;46(6):1710-3.

Xu L, Guo ZN, Yang Y, Xu J, Burchell SR, Tang J, Zhang J, Xu J, Zhang JH. Angiopoietin-like 4: A double-edged sword in Atherosclerosis and Ischemic Stroke? Exp Neurol. 2015 May 29. pii: S0014-4886(15)30007-8.

Reis C, Wang Y, Akyol O, Ho WM, Ii RA, Stier G, Martin R, Zhang JH. What's New in Traumatic Brain Injury: Update on Tracking, Monitoring and Treatment. Int J Mol Sci. 2015 May 26;16 (6):11903-11965. Review.

Li B, He Y, Xu L, Hu Q, Tang J, Chen Y, Tang J, Feng H, Zhang JH. Progranulin Reduced Neuronal Cell Death by Activation of Sortilin 1 Signaling Pathways after Subarachnoid Hemorrhage in Rats. Crit Care Med. 2015 May 22.

Chen Y, Li Q, Tang J, Feng H, Zhang JH. The evolving roles of pericyte in early brain injury after subarachnoid hemorrhage. Brain Res. 2015 May 14. pii: S0006-8993(15)00389-3.

Klebe D, McBride D, Flores JJ, Zhang JH, Tang J. Modulating the Immune Response Towards a Neuroregenerative Peri-injury Milieu After Cerebral Hemorrhage. J Neuroimmune Pharmacol. 2015 May 7.

McBride DW, Klebe D, Tang J, Zhang JH. Correcting for Brain Swelling's Effects on Infarct Volume Calculation after Middle Cerebral Artery Occlusion in Rats. Transl Stroke Res. 2015 May 3.

Liu F, Chen Y, Hu Q, Li B, Tang J, He Y, Guo Z, Feng H, Tang J, Zhang JH. MFGE8/Integrin β3 pathway alleviates apoptosis and inflammation in early brain injury after subarachnoid hemorrhage in rats. Exp Neurol. 2015 May 1. pii: S0014-4886(15)00130-2.

Tan L, Margaret B, Zhang JH, Hu R, Yin Y, Cao L, Feng H, Zhang Y. Efficacy and Safety of Cilostazol Therapy in Ischemic Stroke: A Meta-analysis. J Stroke Cerebrovasc Dis. 2015 May;24 (5):930-8.

Yang F, Wang Z, Zhang JH, Tang J, Liu X, Tan L, Huang QY, Feng H. Receptor for advanced glycation end-product antagonist reduces blood-brain barrier damage after intracerebral hemorrhage. Stroke. 2015 May;46 (5):1328-36.

Wang Y, Reis C, Applegate R 2nd, Stier G, Martin R, Zhang JH. Ischemic conditioning-induced endogenous brain protection: Applications pre-, per- or post-stroke. Exp Neurol. 2015 Apr 18. pii: S0014-4886(15)00123-5.

Chen Y, Feng H, Zhang JH. Response to letter regarding article, "Norrin protected blood-brain barrier via frizzled-4/β-catenin pathway after subarachnoid hemorrhage in rats". Stroke. 2015 Apr;46(4):e91.

Chen S, Chen Y, Xu L, Matei N, Tang J, Feng H, Zhang JH. Venous system in acute brain injury: Mechanisms of pathophysiological change and function. Exp Neurol. 2015 Mar 14. pii: S0014-4886(15)00074-6.

Bian H, Hu Q, Liang X, Chen D, Li B, Tang J, Zhang JH. Hyperbaric oxygen preconditioning attenuates hemorrhagic transformation through increasing PPARγ in hyperglycemic MCAO rats. Exp Neurol. 2015 Mar;265:22-9.

Chen Y, Luo C, Zhao M, Li Q, Hu R, Zhang JH, Liu Z, Feng H. Administration of a PTEN inhibitor BPV(pic) attenuates early brain injury via modulating AMPA receptor subunits after subarachnoid hemorrhage in rats. Neurosci Lett. 2015 Feb 19;588:131-6.

Chen Y, Zhang Y, Tang J, Liu F, Hu Q, Luo C, Tang J, Feng H, Zhang JH. Norrin protected blood-brain barrier via frizzled-4/β-catenin pathway after subarachnoid hemorrhage in rats. Stroke. 2015 Feb;46(2):529-36.

Zheng Y, Hu Q, Manaenko A, Zhang Y, Peng Y, Xu L, Tang J, Tang J, Zhang JH. 17β-Estradiol attenuates hematoma expansion through estrogen receptor α/silent information regulator 1/nuclear factor-kappa b pathway in hyperglycemic intracerebral hemorrhage mice. Stroke. 2015 Feb;46(2):485-91.

Chen S, Yang Q, Chen G, Zhang JH. An update on inflammation in the acute phase of intracerebral hemorrhage. Transl Stroke Res. 2015 Feb;6(1):4-8.

Li L, McBride DW, Doycheva D, Dixon BJ, Krafft PR, Zhang JH, Tang J. G-CSF attenuates neuroinflammation and stabilizes the blood-brain barrier via the PI3K/Akt/GSK-3β signaling pathway following neonatal hypoxia-ischemia in rats. Exp Neurol. 2015 Jan 10. pii: S0014-4886(15)00005-9.

Chen S, Wu H, Tang J, Zhang J, Zhang JH. Neurovascular events after subarachnoid hemorrhage: focusing on sub-cellular organelles. Acta Neurochir Suppl. 2015;120:39-46.

Solaroglu I, Digicaylioglu M, Keles GE, Zhang JH. New missions for an old agent: granulocyte-colony stimulating factor in the treatment of stroke patients. Curr Med Chem. 2015;22(10):1302-9.

Souvenir R, Doycheva D, Zhang JH, Tang J. Erythropoietin in stroke therapy: friend or foe. Curr Med Chem. 2015;22(10):1205-13.

Lekic T, Klebe D, Poblete R, Krafft PR, Rolland WB, Tang J, Zhang JH. Neonatal brain hemorrhage (NBH) of prematurity: translational mechanisms of the vascular-neural network. Curr Med Chem. 2015;22(10):1214-38.

Li L, Klebe D, Doycheva D, McBride DW, Krafft PR, Flores J, Zhou C, Zhang JH, Tang J. G-CSF ameliorates neuronal apoptosis through GSK-3β inhibition in neonatal hypoxia-ischemia in rats. Exp Neurol. 2015 Jan;263:141-9.

Zhan Y, Krafft PR, Lekic T, Ma Q, Souvenir R, Zhang JH, Tang J. Imatinib preserves blood-brain barrier integrity following experimental subarachnoid hemorrhage in rats. J Neurosci Res. 2015 Jan;93(1):94-103.

Liu F, Hu Q, Li B, Manaenko A, Chen Y, Tang J, Guo Z, Tang J, Zhang JH. Recombinant milk fat globule-EGF factor-8 reduces oxidative stress via Integrin β3/nuclear factor erythroid 2-related factor 2/heme oxygenase pathway in subarachnoid hemorrhage rats. Stroke. 2014 Dec;45(12):3691-7.

Fujii M, Sherchan P, Soejima Y, Hasegawa Y, Flores J, Doycheva D, Zhang JH. Response to Letter to the editor from Dr. Dale Ding: Abrogation of cerebral edema and vascular inflammation following subarachnoid hemorrhage by cannabinoid receptor activation. J Neurol Sci. 2014 Nov 15;346(1-2):338.

Fujii M, Sherchan P, Soejima Y, Hasegawa Y, Flores J, Doycheva D, Zhang JH. Cannabinoid receptor type 2 agonist attenuates apoptosis by activation of phosphorylated CREB-Bcl-2 pathway after subarachnoid hemorrhage in rats. Exp Neurol. 2014 Nov;261:396-403.

Liang X, Hu Q, Li B, McBride D, Bian H, Spagnoli P, Chen D, Tang J, Zhang JH. Follistatin-like 1 attenuates apoptosis via disco-interacting protein 2 homolog A/Akt pathway after middle cerebral artery occlusion in rats. Stroke. 2014 Oct;45(10):3048-54.

Doycheva DM, Hadley T, Li L, Applegate RL 2nd, Zhang JH, Tang J.Anti-neutrophil antibody enhances the neuroprotective effects of G-CSF by decreasing number of neutrophils in hypoxic ischemic neonatal rat model. Neurobiol Dis. 2014 Sep;69:192-9.

Klebe D, Krafft PR, Hoffmann C, Lekic T, Flores JJ, Rolland W, Zhang JH. Acute and delayed deferoxamine treatment attenuates long-term sequelae after germinal matrix hemorrhage in neonatal rats. Stroke. 2014 Aug;45(8):2475-9.

Zhang JH. Vascular neural network in subarachnoid hemorrhage. Transl Stroke Res. 2014 Aug;5(4):423-8.

Fujii M, Sherchan P, Krafft PR, Rolland WB, Soejima Y, Zhang JH. Cannabinoid  type 2 receptor stimulation attenuates brain edema by reducing cerebral leukocyte infiltration following subarachnoid hemorrhage in rats. J Neurol Sci. 2014 Jul 15;342(1-2):101-6.

Yang Z, Zhao T, Zou Y, Zhang JH, Feng H. Curcumin inhibits microglia inflammation and confers neuroprotection in intracerebral hemorrhage. Immunol Lett. 2014 Jul;160(1):89-95.

Ma Q, Chen S, Hu Q, Feng H, Zhang JH, Tang J. Reply: To PMID 24273204. Ann Neurol. 2014 Jun;75(6):972-3.

Hu Q, Liang X, Chen D, Chen Y, Doycheva D, Tang J, Tang J, Zhang JH. Delayed  hyperbaric oxygen therapy promotes neurogenesis through reactive oxygen species/hypoxia-inducible factor-1α/β-catenin pathway in middle cerebral artery occlusion rats. Stroke. 2014 Jun;45(6):1807-14.

Krafft PR, McBride DW, Lekic T, Rolland WB, Mansell CE, Ma Q, Tang J, Zhang JH. Correlation between sub-acute sensorimotor deficits and brain edema in two mouse models of intracerebral hemorrhage. Behav Brain Res. 2014 May 1;264:151-60.

Flores JJ, Zhang Y, Klebe DW, Lekic T, Fu W, Zhang JH. Small molecule inhibitors in the treatment of cerebral ischemia. Expert Opin Pharmacother. 2014 Apr;15(5):659-80.

Asadamongkol B, Zhang JH. The development of hyperbaric oxygen therapy for skin rejuvenation and treatment of photoaging. Med Gas Res. 2014 Apr 1;4(1):7.

Leak RK, Zheng P, Ji X, Zhang JH, Chen J. From apoplexy to stroke: historical perspectives and new research frontiers. Prog Neurobiol. 2014 Apr;115:1-5.

Chen S, Feng H, Sherchan P, Klebe D, Zhao G, Sun X, Zhang J, Tang J, Zhang JH. Controversies and evolving new mechanisms in subarachnoid hemorrhage. Prog Neurobiol. 2014 Apr;115:64-91.

Li Q, Khatibi N, Zhang JH. Vascular neural network: the importance of vein drainage in stroke. Transl Stroke Res. 2014 Apr;5(2):163-6.

Manaenko A, Lekic T, Barnhart M, Hartman R, Zhang JH. Inhibition of transforming growth factor-β attenuates brain injury and neurological deficits in a rat model of germinal matrix hemorrhage. Stroke. 2014 Mar;45(3):828-34.

Nowrangi DS, Tang J, Zhang JH. Argon gas: a potential neuroprotectant and promising medical therapy. Med Gas Res. 2014 Feb 17;4(1):3

Wang M, Zhang JH, Applegate RL 2nd. Adverse effect of inhalational anesthetics on the developing brain. Med Gas Res. 2014 Feb 14;4(1):2.

Ma Q, Chen S, Hu Q, Feng H, Zhang JH, Tang J. NLRP3 inflammasome contributes  to inflammation after intracerebral hemorrhage. Ann Neurol. 2014 Feb;75(2):209-19

Altay O, Suzuki H, Hasegawa Y, Ostrowski RP, Tang J, Zhang JH. Isoflurane on brain inflammation. Neurobiol Dis. 2014 Feb;62:365-71.

Lin CL, Dumont AS, Zhang JH, Zuccarello M, Muroi C. Cerebral vasospasm after  aneurysmal subarachnoid hemorrhage: mechanism and therapies. Biomed Res Int. 2014;2014:679014.

Chen S, Li Q, Wu H, Krafft PR, Wang Z, Zhang JH. The harmful effects of subarachnoid hemorrhage on extracerebral organs. Biomed Res Int. 2014;2014:858496.

Hu Q, Vakhmjanin A, Li B, Tang J, Zhang JH. Hyperbaric oxygen therapy fails to reduce hydrocephalus formation following subarachnoid hemorrhage in rats. Med Gas Res. 2014 Jul 9;4:12.

Yang Z, Zhao TZ, Zou YJ, Zhang JH, Feng H. Hypoxia Induces autophagic cell death through hypoxia-inducible factor 1α in microglia. PLoS One. 2014 May 12;9(5):e96509..

Drunalini Perera PN, Hu Q, Tang J, Li L, Barnhart M, Doycheva DM, Zhang JH, Tang J. Delayed remote ischemic post-conditioning improves long term sensory motor deficits in a neonatal hypoxic ischemic rat model. PLoS One. 2014 Feb 28;9(2):e90258.

Chen S, Zhu Z, Klebe D, Bian H, Krafft PR, Tang J, Zhang J, Zhang JH. Role of P2X purinoceptor 7 in neurogenic pulmonary edema after subarachnoid hemorrhage in rats. PLoS One. 2014 Feb 12;9(2):e89042.

Chen S, Ma Q, Krafft PR, Hu Q, Rolland W 2nd, Sherchan P, Zhang J, Tang J, Zhang JH. P2X7R/cryopyrin inflammasome axis inhibition reduces neuroinflammation after SAH. Neurobiol Dis. 2013 Jun 29.

Hou J, Zhang JH. Does prevention of vasospasm in subarachnoid hemorrhage improve clinical outcome? No. Stroke. 2013 Jun;44(6 Suppl 1):S34-6.

Dixon BJ, Tang J, Zhang JH. The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance. Med Gas Res. 2013 May 16;3(1):10.

Lapchak PA, Zhang JH, Noble-Haeusslein LJ. RIGOR Guidelines: Escalating STAIR and STEPS for Effective Translational Research. Transl Stroke Res. 2013 Jun;4(3):279-285.

Chen CH, Jiang Z, Yan JH, Yang L, Wang K, Chen YY, Han JY, Zhang JH, Zhou CM. The Involvement of Programmed Cell Death 5 (PDCD5) in the Regulation of Apoptosis in Cerebral Ischemia/Reperfusion Injury. CNS Neurosci Ther. 2013 May 3.

Fathali N, Ostrowski RP, Hasegawa Y, Lekic T, Tang J, Zhang JH. Splenic Immune Cells In Experimental Neonatal Hypoxia-ischemia. Transl Stroke Res. 2013 Apr 1;4(2):208-219.

Krafft PR, Caner B, Klebe D, Rolland WB, Tang J, Zhang JH. PHA-543613 preserves blood-brain barrier integrity after intracerebral hemorrhage in mice. Stroke. 2013 May;44(5):1410-7.

Doycheva D, Shih G, Chen H, Applegate R, Zhang JH, Tang J. Granulocyte-colony stimulating factor in combination with stem cell factor confers greater neuroprotection after hypoxic-ischemic brain damage in the neonatal rats than a solitary treatment. Transl Stroke Res. 2013 Apr 1;4(2):171-178.

Yan J, Manaenko A, Chen S, Klebe D, Ma Q, Caner B, Fujii M, Zhou C, Zhang JH. Role of SCH79797 in maintaining vascular integrity in rat model of subarachnoid hemorrhage. Stroke. 2013 May;44(5):1410-7.

Soejima Y, Hu Q, Krafft PR, Fujii M, Tang J, Zhang JH. Hyperbaric oxygen preconditioning attenuates hyperglycemia-enhanced hemorrhagic transformation by inhibiting matrix metalloproteinases in focal cerebral ischemia in rats. Exp Neurol. 2013 Mar 26.

Mu J, Ostrowski RP, Krafft PR, Tang J, Zhang JH. Serum leptin levels decrease after permanent MCAo in the rat and remain unaffected by delayed hyperbaric oxygen therapy. Med Gas Res. 2013 Mar 19;3(1):8.

Ma Q, Chen S, Klebe D, Zhang JH, Tang J. Adhesion molecules in CNS disorders: biomarker and therapeutic targets. CNS Neurol Disord Drug Targets. 2013 May 1;12(3):392-404.

Manaenko A, Lekic T, Ma Q, Zhang JH, Tang J. Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. Crit Care Med. 2013 May;41(5):1266-75.

Esencan E, Yuksel S, Tosun YB, Robinot A, Solaroglu I, Zhang JH. XENON in medical area: emphasis on neuroprotection in hypoxia and anesthesia. Med Gas Res. 2013 Feb 1;3(1):4.

Wang T, Wu X, Yin C, Klebe D, Zhang JH, Qin X. CRMP-2 is involved in axon growth inhibition induced by RGMa in vitro and in vivo. Mol Neurobiol. 2013 Jun;47(3):903-13.

Rolland WB, Lekic T, Krafft PR, Hasegawa Y, Altay O, Hartman R, Ostrowski R, Manaenko A, Tang J, Zhang JH. Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage. Exp Neurol. 2013 Mar;241:45-55.

Lekic T, Rolland W, Manaenko A, Krafft PR, Kamper JE, Suzuki H, Hartman RE, Tang J, Zhang JH. Evaluation of the hematoma consequences, neurobehavioral profiles, and histopathology in a rat model of pontine hemorrhage. J Neurosurg. 2013 Feb;118(2):465-77.

Mu J, Ostrowski RP, Soejima Y, Rolland WB, Krafft PR, Tang J, Zhang JH. Delayed hyperbaric oxygen therapy induces cell proliferation through stabilization of cAMP responsive element binding protein in the rat model of MCAO-induced ischemic brain injury. Neurobiol Dis. 2013 Mar;51:133-43.

Manaenko A, Sun X, Kim CH, Yan J, Ma Q, Zhang JH. PAR-1 antagonist SCH79797 ameliorates apoptosis following surgical brain injury through inhibition of ASK1-JNK in rats. Neurobiol Dis. 2013 Feb;50:13-20.

Ayer RE, Ostrowski RP, Sugawara T, Ma Q, Jafarian N, Tang J, Zhang JH. Statin-induced T-lymphocyte modulation and neuroprotection following experimental subarachnoid hemorrhage. Acta Neurochir Suppl. 2013;115:259-66.

Caner B, Hou J, Altay O, Fuj M 2nd, Zhang JH. Transition of research focus from vasospasm to early brain injury after subarachnoid hemorrhage. J Neurochem. 2012 Nov;123 Suppl 2:12-21.

Zhang JH, Badaut J, Tang J, Obenaus A, Hartman R, Pearce WJ. The vascular neural network--a new paradigm in stroke pathophysiology. Nat Rev Neurol. 2012 Dec;8(12):711-6.

Krafft PR, Rolland WB, Duris K, Lekic T, Campbell A, Tang J, Zhang JH. Modeling intracerebral hemorrhage in mice: injection of autologous blood or bacterial collagenase. J Vis Exp. 2012 Sep 22;(67):e4289.

Hou J, Manaenko A, Hakon J, Hansen-Schwartz J, Tang J, Zhang JH. Liraglutide, a long-acting GLP-1 mimetic, and its metabolite attenuate inflammation after intracerebral hemorrhage. J Cereb Blood Flow Metab. 2012 Dec;32(12):2201-10.

He Z, Ostrowski RP, Sun X, Ma Q, Tang J, Zhang JH. Targeting C/EBP homologous protein with siRNA attenuates cerebral vasospasm after experimental subarachnoid hemorrhage. Exp Neurol. 2012 Dec;238(2):218-24.

Van Allen NR, Krafft PR, Leitzke AS, Applegate RL 2nd, Tang J, Zhang JH. The role of Volatile Anesthetics in Cardioprotection: a systematic review. Med Gas Res. 2012 Aug 28;2(1):22.

Charles MS, Ostrowski RP, Manaenko A, Duris K, Zhang JH, Tang J. Role of the pituitary–adrenal axis in granulocyte-colony stimulating factor-induced neuroprotection against hypoxia–ischemia in neonatal rats. Neurobiol Dis. 2012 Jul;47(1):29-37.

Altay O, Suzuki H, Hasegawa Y, Caner B, Krafft PR, Fujii M, Tang J, Zhang JH. Isoflurane attenuates blood-brain barrier disruption in ipsilateral hemisphere after subarachnoid hemorrhage in mice. Stroke. 2012 Sep;43(9):2513-6.

Krafft PR, Bailey EL, Lekic T, Rolland WB, Altay O, Tang J, Wardlaw JM, Zhang JH, Sudlow CL. Etiology of stroke and choice of models. Int J Stroke. 2012 Jul;7(5):398-406.

Liu W, Liu K, Tao H, Chen C, Zhang JH, Sun X. Hyperoxia preconditioning: the next frontier in neurology? Neurol Res. 2012 Jun;34(5):415-21.

Benggon M, Chen H, Applegate R, Martin R, Zhang JH. Effect of dexmedetomidine on brain edema and neurological outcomes in surgical brain injury in rats. Anesth Analg. 2012 Jul;115(1):154-9.

Lekic T, Manaenko A, Rolland W, Krafft PR, Peters R, Hartman RE, Altay O, Tang J, Zhang JH. Rodent neonatal germinal matrix hemorrhage mimics the human brain injury, neurological consequences, and post-hemorrhagic hydrocephalus. Exp Neurol. 2012 Jul;236(1):69-78.

Soejima Y, Ostrowski RP, Manaenko A, Fujii M, Tang J, Zhang JH. Hyperbaric oxygen preconditioning attenuates hyperglycemia enhanced hemorrhagic transformation after transient MCAO in rats. Med Gas Res. 2012 Apr 11;2(1):9.

Altay O, Hasegawa Y, Sherchan P, Suzuki H, Khatibi NH, Tang J, Zhang JH. Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice. Crit Care Med. 2012 Jun;40(6):1908-13.

Sehba FA, Hou J, Pluta RM, Zhang JH. The importance of early brain injury after subarachnoid hemorrhage. Prog Neurobiol. 2012 Apr;97(1):14-37.

Li B, Luo C, Tang W, Chen Z, Li Q, Hu B, Lin J, Zhu G, Zhang JH, Feng H. Role of HCN channels in neuronal hyper-excitability after subarachnoid hemorrhage in rats. J Neurosci. 2012 Feb 29;32(9):3164-75.

Y. Zhan, C. Chen, H. Suzuki, Q. Hu, X. Zhi, JH. Zhang. Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. Critical Care Med. Vol. 40 (4) 2012

RE. Ayer, N. Jafarian, W. Chen, RL. 2nd Applegate, AR. Colohan, JH. Zhang. Preoperative mucosal tolerance to brain antigens and a neuroprotective immune response following surgical brain injury. J. Neurosurg 116(1): 246-53, 2012

B. Huang, P.R. Krafft, Q. Ma, W.B. Rolland, B. Caner, T. Lekic, A. Manaenko, M. Le, J. Tang, J.H. Zhang. Fibroblast growth factors preserve blood-brain barrier integrity through RhoA inhibition after intracerebral hemorrhage in mice. Neurobiol Dis.: 1-11, 2012

M. Fujii, K. Duris, O. Altay, Y. Soejima, P. Sherchan, J.H. Zhang. Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats. Neurochem Int. 60 (3): 327-33, 2011

M.S. Charles, J.H. Zhang. Sleep a therapeutic target for stroke? Exp Neurol. : 1-4, 2011

P.R. Krafft, O. Altay, W.B. Rolland, K. Duris, T. Lekic, J. Tang, J.H. Zhang. α7 Nicotinic Acetylcholine Receptor Agonism Confers Neuroprotection Through GSK-3β Inhibition in a Mouse Model of Intracerebral Hemorrhage. Stroke. 43(3): 844-50, 2011  

Y. Hasegawa, H. Suzuki, O. Altay, H. Chen, J.H. Zhang. Treatment with sodium orthovanadate reduces blood-brain barrier disruption via phosphatase and tensin homolog deleted on chromosome 10 (PTEN) phosphorylation in experimental subarachnoid hemorrhage. J Neurosci Res. 90(3): 691-7, 2012

CHOP Silencing Reduces Acute Brain Injury in the Rat Model of Subarachnoid Hemorrhage. Stroke. 43(2): 484-90, 2012

Ostrowski RP, Zhang JH. Hyperbaric Oxygen for Cerebral Vasospasm and Brain Injury Following Subarachnoid Hemorrhage. Transl Stroke Res. 2011 Sep 1;2(3):316-327.

H. Chen, F. Spagnoli, M. Burris, W.B. Rolland, A. Fajilan, H. Dou, J. Tang, J.H. Zhang. Nanoerythropoietin Is 10-Times More Effective Than Regular Erythropoietin in Neuroprotection in a Neonatal Rat Model of Hypoxia and Ischemia. Stroke.43(3): 884-7, 2011

J.M. Eckermann, W. Chen, V. Jadhav, F.P. Hsu, A.R Colohan, J. Tang, J.H. Zhang. Hydrogen is neuroprotective against surgically induced brain injury. Med Gas Res. 1(1): 1-6, 2011

R.P. Ostrowski, T. Lo, J.H. Zhang. The pacific chapter annual meeting of the undersea & hyperbaric medical society. Med Gas Res. 1(1): 1-6, 2011

J. Mu, P.R. Krafft, J.H. Zhang. Hyperbaric oxygen therapy promotes neurogenesis: where do we stand? Med Gas Res. 1(1): 1-7, 2011

J.H. Zhang. Welcome to medical gas research. Med Gas Res. (1): 1-3, 2011

R.E. Ayer, N. Jafarian, W. Chen, R.L. Applegate 2nd, A.R. Colohan, J.H. Zhang. Preoperative mucosal tolerance to brain antigens and a neuroprotective immune response following surgical brain injury. J Neurosurg. 116(1): 246-53, 2012

P. Sherchan, T. Lekic, H. Suzuki, Y. Hasegawa, W. Rolland, K. Duris, Y. Zhan, J. Tang, J.H. Zhang. Minocycline improves functional outcomes, memory deficits, and histopathology after endovascular perforation-induced subarachnoid hemorrhage in rats. J Neurotrauma. 28(12): 2503-12, 2011

K. Duris, A. Manaenko, H. Suzuki, W.B. Rolland, P.R. Krafft, J.H. Zhang. α7 nicotinic acetylcholine receptor agonist PNU-282987 attenuates early brain injury in a perforation model of subarachnoid hemorrhage in rats. Stroke. 42(12): 3530-6, 2011 Dec

H. Chen, M. Burris, A. Fajilan, F. Spagnoli, J. Tang, J.H. Zhang. Prolonged Exposure to Isoflurane Ameliorates Infarction Severity in the Rat Pup Model of Neonatal Hypoxia-ischemia. Transl Stroke Res. 2(3): 382-390, 2011 Sep

R. Souvenir, N. Fathali, R.P. Ostrowski, T. Lekic, J.H. Zhang, J. Tang. Tissue inhibitor of matrix metalloproteinase-1 mediates erythropoietin-induced neuroprotection in hypoxia ischemia. Neurobiol Dis. 44(1): 28-37, 2011

K. Duris, A. Manaenko, H. Suzuki, W. Rolland, J. Tang, J.H. Zhang. Sampling of CSF via the Cisterna Magna and Blood Collection via the Heart Affects Brain Water Content in a Rat SAH Model. Transl Stroke Res. 2(2): 232-237, 2011

N.H. Khatibi, Q. Ma, W. Rolland, R. Ostrowski, N. Fathali, R. Martin, R. Applegate, G. Stier, J. Tang, J.H. Zhang. Isoflurane post-treatment reduces brain injury after an intracerebral hemorrhagic stroke in mice. Anesth Analg. 113(2): 343-8, 2011

W. Chen, Q. Ma, H. Suzuki, R. Hartman, J. Tang, J.H. Zhang. Osteopontin reduced hypoxia-ischemia neonatal brain injury by suppression of apoptosis in a rat pup model. Stroke. 42(3): 764-9, 2011

A. Manaenko, N. Fathali, N.H. Khatibi, T. Lekic, Y. Hasegawa, R. Martin, J. Tang, J.H. Zhang. Arginine-vasopressin V1a receptor inhibition improves neurologic outcomes following an intracerebral hemorrhagic brain injury. Neurochem Int. 58(4): 542-8, 2011

Y. Hasegawa, H. Suzuki, O. Altay, J.H. Zhang. Preservation of tropomyosin-related kinase B (TrkB) signaling by sodium orthovanadate attenuates early brain injury after subarachnoid hemorrhage in rats. Stroke. 42(2): 477-83, 2011

Y. Zhou, N. Fathali, T. Lekic, R.P. Ostrowski, C. Chen, R.D. Martin, J. Tang, J.H. Zhang. Remote limb ischemic post-conditioning protects against neonatal hypoxic-ischemic brain injury in rat pups by the opioid receptor/Akt pathway. Stroke. 42(2): 439-44, 2011

A. Manaenko, H. Chen, J. Kammer, J.H. Zhang, J. Tang. Comparison Evans Blue injection routes: Intravenous versus intraperitoneal, for measurement of blood-brain barrier in a mice hemorrhage model. J Neurosci Methods. 195(2): 206-10 2011

O. Cheng, R.P. Ostrowski, B. Wu, W. Liu, C. Chen, J.H. Zhang. Cyclooxygenase-2 mediates hyperbaric oxygen preconditioning in the rat model of transient global cerebral ischemia. Stroke. 42(2): 484-90, 2011

T. Lekic, W. Rolland, R. Hartman, J. Kamper, H. Suzuki, J. Tang, J.H. Zhang. Characterization of the brain injury, neurobehavioral profiles, and histopathology in a rat model of cerebellar hemorrhage Exp Neurol. 227(1): 96-103, 2011

Q. Ma, A. Manaenko, N.H. Khatibi, W. Chen, J.H. Zhang, J. Tang. Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice. J Cereb Blood Flow Metab. 31(3): 881-93, 2011

Y. Zhan, C. Chen, H. Suzuki, Q. Hu, X. Zhi, J.H. Zhang.  Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. Crit Care Med. 2012 Feb

P. Sherchan, T. Lekic, H. Suzuki, Y. Hasegawa, W. Rolland, K. Duris, Y. Zhan, J. Tang, J.H. Zhang. Minocycline improves functional outcomes, memory deficits, and histopathology after endovascular perforation-induced subarachnoid hemorrhage in rats. J Neurotrauma. 28(12): 2503-12, 2011

A. Manaenko, N. Fathali, H. Chen, H. Suzuki, S. Williams, J.H. Zhang, J. Tang. Heat shock protein 70 up-regulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage. Neurochem Int. 57(7): 844-50, 2010

H. Suzuki, Y. Hasegawa, W. Chen, K. Kanamaru, J.H. Zhang.  Recombinant osteopontin in cerebral vasospasm after subarachnoid hemorrhage. Ann Neurol. 68(5): 650-60, 2010

MS Charles, J.H. Zhang. Sleep a therapeutic target for stroke. Experimental Neurology 234 (1): 1-4, 2012

Q. Ma, B. Huang, N. Khatibi, W. Rolland 2nd, H. Suzuki, J.H. Zhang, J. Tang. PDGFR-α inhibition preserves blood brain barrier after intracerebral hemorrhage. Ann Neurol. 70(6): 920-31, 2011

 Z. He, RP. Ostrowski, X. Sun, Q. Ma, B. Huang, Y. Zhan, J.H. Zhang. CHOP silencing reduces acute brain injury in the rat model of sbarachnoid hemorrhage. Stroke 43(2): 484-490, 2012

K Duris, A Manaenko, H Suzuki, WB Rolland, PR Krafft, JH Zhang. α7 Nicotinic acetylcholine receptor agonist PNU-282987 attenuates early brain injury in a perforation model of subarachnoid hemorrhage in rats. Stroke 42(12):3530-6, 2011

R. Souvenir, N. Fathali, RP. Ostrowski, T. Lekic, JH. Zhang, J. Tang. Tissue inhibitor of matrix metalloproteinase-1 mediates erythropoietin-induced neuroprotection in hypoxia ischemia. Neuobiol Dis. 44(1): 28-37, 2011

Editor for Books | Original Article | Review | Editorial/Letter | Journal Supplement

Editor for Books

Early Brain Injury or Vasospasm, a Crossroad for Subarachnoid Hemorrhage Research and Treatment. Editors: Hua Feng, John H. Zhang. Springer Wien New York. Acta Neurochirurgica Supplement xxx, pp1xxxx, 2010

Intracerebral Hemorrhage Research: From Bench to Bedside. Editors: John H. Zhang, Austin Colohan. Springer Wien New York. Acta Neurochirurgica Supplement xxx, pp1xxxx, 2010

Animal Models of Acute Neurological Injury II: Injury and Mechanistic Assessments. Editors: Jun Chen, Xiaoming Xu, Zao C. Xu, John H. Zhang. Springer pp xxxx, 2010

Original Article

H. Suzuki, R. Ayer, T. Sugawara, W. Chen, T. Sozen, Y. Hasegawa, K. Kanamaru, J. H. Zhang. Protective effects of recombinant osteopontin on early brain injury after subarachnoid hemorrhage in rats. Critical Care Med 38 (2): 612-8, 2010

Y. Hasegawa, H. Suzuki, T. Sozen, W. Rolland, J. H. Zhang. Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats. Stroke 41 (2): 368-74, 2010

Y. Wang, X. Wang, Y. Kong, J.H. Zhang, Q. Zeng. The Great Chinese Famine Leads to Shorter and Overweight Females in Chongqing Chinese Population after 50 Years. Obesity (Silver Spring) 18 (3): 588-92, 2010

N. Fathali, R. Ostrowski, T. Lekic, V. Jadhav, W. Tong, J. Tang, J. Zhang. Cyclooxygenase-2 Inhibition provides Lasting Protection against Hypoxia Ischemia Induced Neonatal Encephalopathy. Critical Care Medicine 38 (2): 572-578, 2010

T. Lekic, R. Hartman, H. Rojas, A. Manaenko, W. Chen, R. Ayer, J. Tang, J. H. Zhang. Protective Effect of Melatonin upon Neuropathology, Striatal Function and Memory Ability after Intracerebral Hemorrhage in Rats. J Neurotrauma 27 (3): 627-637, 2010

N. Sakata, N. Chan, P. Hayes, R. Ostrowski, J. Mace, R. Peverini, R. Chinnock, A. Obenaus, J. Zhang, E. Hathout. Hyperbaric Oxygen Treatment Improves Early Post-Transplant Islet Function. Pediatric Diabetes 2010 Feb 7

C. Chen, R. P. Ostrowski, C. Zhou, J. H. Zhang. Suppression of HIF-1α and its Downstream Genes Reduces Hyperglycemia-Enhanced Hemorrhagic Transformation in a Rat Model of Cerebral Ischemia. J Neurosci Res 2010 Feb 12

C. Yan, J. Eckermann, X. Qin, J. H. Zhang. Ten Years Clinical Epidemiological Trends of Intracerebral Hemorrhage in Chongqing China. Neurological Research 2010

R. Ayer, W. Chen, T. Sugawara, H. Suzuki, J. H. Zhang. Role of Gap Junctions in Early Brain Injury following Subarachnoid Hemorrhage. Brain Research 1315: 150-158, 2010

O. Cheng, R. Ostrowski, W. Liu J. H. Zhang. Activation of Liver X Receptor Reduces Global Ishcmia Brain Injury by Reduction of Nuclear Factor-kB. Neuroscience 2010

B. Huang, N. Khatibi, L. Tong, P. Yan, P. Xie, J.H. Zhang. Magnesium Sulfate Treatment Improves Outcome in Patients with Subarachnoid Hemorrhage: A Meta-analysis Study. Translational Stroke Research 2010

Z. Guo, X. Sun, Z. He, Y. Jiang, X. Zhang, J. H. Zhang. Matrix Metalloproteinase-9 Potentiates Early Brain Injury after Subarachnoid Hemorrhage. Neurological Res 2010

J. Li, C. Wang, J.H. Zhang, J. Cai, Y. Cao, X. Sun. Hydrogen-rich Saline Improves Memory Function in a Rat Model of Amyloid-beta-induced Alzheimer’s Disease by Reduction of Oxidative Stress. Brain Research 2010

C. Chen, Q. Chen, Y. Mao, S. Xu, C. Xia, X. Shi, J. H. Zhang, H. Yuan, & X. Sun. Hydrogen-rich saline protects against spinal cord injury in rats. Neurochemical Research 2010

Y. Zhou, T. Lekic, N. Fathali, R. Ostrowski, R. Martin, J. Tang, J.H. Zhang. Isoflurane Post-treatment Reduces Neonatal Hypoxic-ischemic Brain Injury in Rats by S1P/PI3K/Akt Pathway. Stroke 2010

N. Fathali, T. Lekic, W. Tong, J.H. Zhang, J. Tang. Long-term Evaluation of Granulocyte-colony Stimulating Factor on Hypoxic-ischemic Brain Injury in Infant Rats. Intensive Care Medicine 2010

B. Wu, Q. Ma, H. Suzuki, C. Chen, W. Liu, J. Tang, J. Zhang. Recombinant Osteopontin Attenuates Brain Injury after Intracerebral Hemorrhage in Mice. Neurocritical Care 2010

C. Chen, A. Manaenko, Y. Zhan, W. Liu, R. Ostrowski, J. Tang, J. H. Zhang. Hydrogen Gas Reduced Acute Hyperglycemia-enhanced Hemorrhagic Transformation in a Focal Ischemia Rat Model. Neuroscience, 2010

H. Suzuki, Y. Hasegawa, K. Kanamaru, J.H. Zhang. Mechanisms of Osteopontin-induced Stabilization of Blood-Brain Barrier Disruption after Subarachnoid Hemorrhage in Rats. Stroke

2010 list

Review

J. Cahill, J.H. Zhang. New Avenues in the Pathogenesis of Subarachnoid Hemorrhage. Hirosaki Med J 60: S157-S163, 2010

Y. Zhou, J. H. Zhang. Advances in Experimental Subarachnoid Hemorrhage Research. Acta Neurochirurgica Supplement 2010

Y. Hasegawa, H. Suzuki, T. Sozen, O. Altay, J. H. Zhang. Neuronal Apoptosis in Early Brain Injury after Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2010

H. Suzuki, Y. Hasegawa, K. Kanamaru, J. H. Zhang. Mitogen-activated Protein Kinases in Cerebral Vasospasm after Subarachnoid Hemorrhage: A Review. Acta Neurochirurgica Supplement 2010

Z. Guo, X. Sun, J. H. Zhang. The Role of Apolipoprotein E in Pathophysiology Following Subarachnoid Hemorrhage: A Review. Acta Neurochirurgica Supplement 2010

2010 list

Editorial/Letter

Y. Hasegawa, H. Suzuki, T. Sozen, W. Rolland, J. Zhang. Response to Letter by Pfeilschifter. Stroke 2010

I. Solaroglu, J.H. Zhang. Commentary: N-acetylcysteine prevents vasospasm after subarachnoid hemorrhage. World Neurosurgery 73 (1): e3, 2010

H. Feng, Y. Mao, J. H. Zhang. Preface: EARLY BRAIN INJURY OR VASOSPASM A Crossroad for Subarachnoid Hemorrhage Research and Treatment. Acta neurochirurgica Supplement 2010

2010 list

Journal Supplement

T. Sozen, R. Tsuchiyama, Y. Hasegawa, H. Suzuki, V. Jadhav, S. Nishizawa, J. H. Zhang. Immunological Response in Early Brain Injury after Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2010

Z.D. Guo, X.C. Sun, J. H. Zhang. Mechanisms of Early Brain Injury after Subarachnoid Hemorrhage: Role of Matrix Metalloproteinase 9. Acta Neurochirurgica Supplement 2010

Y. Hasegawa, H. Suzuki, P. Sherchan, Y. Zhan, K. Duris, J. H. Zhang. Tyrosine Phosphatase Inhibition Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Rats. Acta Neurochirurgica Supplement 2010

Z.D. Guo, H. T. Wu, X. C. Sun, X. D. Zhang, J. H. Zhang. Protection of Minocycline on Early Brain Injury after Subarachnoid Hemorrhage in Rats. Acta Neurochirurgica Supplement 2010

H. Suzuki, R. Ayer, T. Sugawara, W. Chen, T. Sozen, Y. Hasegawa, K. Kanamaru, J. H. Zhang. Role of Osteopontin in Early Brain Injury after Subarachnoid Hemorrhage in Rats. Acta Neurochirurgica Supplement 2010

Z.D. Guo, X. D. Zhang, H.T. Wu, B. Lin, X. C. Sun, J. H. Zhang. Matrix metalloproteinase 9 inhibition Reduces Early Brain Injury in Cortex after Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2010

C. Luo, B. Yi, Z. Chen, W. Tang, Y. Chen, R. Hu, Z. Liu, H. Feng, J. H. Zhang. Pkgiα Inhibits the Proliferation of Cerebral Arterial Smooth Muscle Cell Induced By Oxyhemoglobin after Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2010

Z. He, X. Sun, Z. Guo, J. H. Zhang. Expression and Role of COMT in a Rat Subarachnoid Hemorrhage Model. Acta Neurochirurgica Supplement 2010

Y. Kong, J. H. Zhang, X. Qin. Perimesencephalic Subarachnoid Hemorrhage: Risk Factors, Clinical Presentations, and Outcomes. Acta Neurochirurgica Supplement 2010

T. Wang, J. H. Zhang, X. Qin. Non-Aneurysm Subarachnoid Hemorrhage in Young Adults. Acta Neurochirurgica Supplement 2010

B. Wu, X. Wang, J. H. Zhang. Cardiac Damage after Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2010

T. Wang, J. H. Zhang, X. Qin. Analysis on Mortality-Associated Factors of Subarachnoid Hemorrhage Patients during Hospitalization. Acta Neurochirurgica Supplement 2010

G. Zhang, J. H. Zhang, Xinyue Qin. Effect of Weekend Admission on In-Hospital Mortality after Subarachnoid Hemorrhage in Chongqing China. Acta Neurochirurgica Supplement 2010

Z. He, X. Sun, Z. Guo, J. H. Zhang. The Correlation between COMT Gene Polymorphism and Early Cerebral Vasospasm after Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2010

G. Zhang, J. H. Zhang, X. Qin. Fever Increased In-Hospital Mortality after Subarachnoid Hemorrhage. Acta Neurochirurgica Supplement 2010

Y. Zhang, T. Wang, J. H. Zhang, J. Zhang, X. Qin. Subarachnoid Hemorrhage in Older Patient Populations in Chongqing China. Acta Neurochirurgica Supplement 2010

T. Sugawara, R. Ayer, V. Jadhav, W. Chen, T. Tsubokawa, J. H. Zhang. Mechanisms of Statin Treatment in Cerebral Vasospasm. Acta Neurochirurgica Supplement 2010

H. Suzuki, Y. Hasegawa, K. Kanamaru, J. H. Zhang. Effect of Recombinant Osteopontin on Cerebral Vasospasm after Subarachnoid Hemorrhage in Rats. Acta Neurochirurgica Supplement 2010

G. Yao, Q. Li, X. Jiang, J. Liu, J. Li, L. Zhang, L. Li, J. H. Zhang, P. Xie. Vasospasm after Subarachnoid Hemorrhage: 3D Rotational Angiography Study. Acta Neurochirurgica Supplement 2010

F. Lv, Q. Li, J. Liao, T. Luo, Y. Shen, J. Li, J. H. Zhang, P. Xie. Detection and Characterization of Intracranial Aneurysms with Dual-energy Subtraction CTA: Comparison with DSA. Acta Neurochirurgica Supplement 2010

X. Li, J. H. Zhang, X. Qin. Intracerebral Hemorrhage and Meteorological Factors. Acta Neurochirurgica Supplemental 2010

Q. Ma; W. Chen; N. Khatibi; J. Tang; J. H. Zhang. History of Pre-clinical Models of Intracerebral Hemorrhage. Acta Neurochirurgica Supplemental 2010

A. Manaenko, H. Chen, J. H. Zhang, J. Tang. Comparison of Different Pre-clinical Models of Intracerebral Hemorrhage. Acta Neurochirurgica Supplemental 2010

W. B. Rolland II, A. Manaenko, T. Lekic, Y. Hasegawa, R. Ostrowski, J. Tang, J. Zhang. FTY720 is Neuroprotective and Improves Functional Outcomes after Intracerebral Hemorrhage in Mice. Acta Neurochirurgica Supplemental 2010

Q. Ma; A. Manaenko; W. Rolland II; W. Chen; J. H. Zhang and J. Tang. Neuroprotection of Vascular Adhesion Protein-1 Inhibition in Intracerebral Hemorrhage Brain Injury in Mouse. Acta Neurochirurgica Supplemental 2010

A. Manaenko, N. Fathali, K. J. Shum, T. Lekic, J. H. Zhang, J. Tang. The Role of Arginine Vasopressin V1a Receptor Antagonist (SR 49059) Upon Neurobehavior and Brain Water Content after a Model of ICH in Mice. Acta Neurochirurgica Supplemental 2010

N. Jafarian; R. Ayer; J. Eckermann; W. Tong; N. Jafarian; R.L. Applegate II, G. Stier; R. Martin; J. Tang, J.H. Zhang. Mucosal Tolerance to Brain Antigens Preserves CNS Immune Privilege and Provides Neuroprotection in Experimental Craniotomy. Acta Neurochirurgica Supplemental 2010

X. Wang, Y. Kong, C. Hui, Y. Wang, J. H. Zhang. Characteristics of Acute Cerebral Hemorrhage about Lipid Metabolism and Glycometabolism among different age groups. Acta Neurochirurgica Supplemental 2010
J. M. Eckermann, W. Chen, W. Tong, V. Jadhav, A. R.T. Colohan, J. H. Zhang. Hydrogen is Neuroprotective against Surgically Induced Brain Injury. Acta Neurochirurgica Supplemental 2010

Y. Hasegawa, S. Yano, M. Morioka, J. H. Zhang, and J. Kuratsu. Endoscopic Surgical Treatment for Pituitary Apoplexy in Three Elderly Patients over the age of 80. Acta Neurochirurgica Supplemental 2010

T. Lekic, A. Manaenko, W. Rolland, J. Tang, J. H. Zhang. A Novel Pre-clinical Model of Germinal Matrix Hemorrhage using Neonatal Rats. Acta Neurochirurgica Supplemental 2010

H. Suzuki, T. Sozen, Y. Hasegawa, W. Chen, J. H. Zhang. Subarachnoid Hemorrhage causes Pulmonary Endothelial Cell Apoptosis and Neurogenic Pulmonary Edema in Mice. Acta Neurochirurgica Supplemental 2010

N. H. Khatibi, V. Jadhav, S. Charles, J. Chiu, J. Buchholz, J. Tang, J. H. Zhang. Capsaicin Pretreatment Provides Neurovascular Protection against Neonatal Hypoxic-ischemic Brain Injury in Rats. Acta Neurochirurgica Supplemental 2010

A. Manaenko, N. Fathali, S. Williams, T. Lekic, J. H. Zhang, J. Tang. Geldanamycin Reduced Brain Injury in Mouse Model of Intracerebral Hemorrhage. Acta Neurochirurgica Supplemental 2010

R. Ayer; V. Jadhav, T. Sugawara, J.H. Zhang. The Neuroprotective Effects of Cyclooxygenase-2 Inhibition in a Mouse Model of Aneurismal Subarachnoid Hemorrhage. Acta Neurochirurgica Supplemental 2010

J. Feng, J. H. Zhang, X. Qin. Timing Pattern of Onset in Patients with Hypertensive Intracerebral Hemorrhage. Acta Neurochirurgica Supplemental 2010

F. Jiang, J. H. Zhang, X. Qin. Weekend Effects in Patients with Intracerebral Hemorrhage. Acta Neurochirurgica Supplemental 2010

X. Hu, J. H. Zhang, X. Qin. The Factors Associated with Mortality of Patients with Hypertensive Intracerebral Hemorrhage during Hospitalization. Acta Neurochirurgica Supplemental 2010

X. Wang, Y. Kong, C. Hui, Y. Wang, J. H. Zhang. The association between Medical Care Costs and Acute Cerebral Hemorrhage. Acta Neurochirurgica Supplemental 2010

Y. Kong, Y. Wang, J. H. Zhang, X. Wang, X. Qin. Acute Hemorrhagic Stroke and Medical Insurance Status in Chongqing Southwest of China. Acta Neurochirurgica Supplemental 2010

Y. Wang, T. Wang, J. H. Zhang, Xinyue Qin. Effects of Early Serum Glucose Level on Prognosis of the Patients with Acute Intracerebral Hemorrhage. Acta Neurochirurgica Supplemental 2010

Z. Guo, J. H. Zhang, X. Qin. Electrolytes Imbalance in Thalamic Hemorrhagic Patients.

Q. Li, X. Qin, J. H. Zhang, J. Yang. The Prognosis Study of 324 Cases with Spontaneous Intracerebral Hemorrhage in Chongqing China. Acta Neurochirurgica Supplemental 2010

Y. Ding, Q. Liu, H. Lei, J. Zhang. The ECG Changes of Acute Cerebral Hemorrhagic Patients. Acta Neurochirurgica Supplemental 2010

Y. Ding, Q. Liu, H. Lei, J. Zhang. The ECG Changes of Acute Subarachnoid Hemorrhagic Patients. Acta Neurochirurgica Supplemental 2010

L. Ran, N. H. Khatibi, X. Qin, J. H. Zhang. Proton Pump Inhibitor Prophyslaxis and the Risk of Nosocomial Pneumonia in Patients with Intracerebral Hemorrhagic Stroke. Acta Neurochirurgica Supplemental 2010

H. Chen, J. Zhang. Cerebral Amyloid Angiopathy-related Microhemorrhages in Alzheimer’s Disease: A Review of Investigative Animal Models. Acta Neurochirurgica Supplemental 2010

A. Manaenko, T. Lekic, C. Sarfo-poku, J. H. Zhang, J. Tang. Arginine Vasopressin V1a Receptor Agonist is Ineffective in Murine Model of ICH. Acta Neurochirurgica Supplemental 2010

T. Lekic, A. Manaenko, W. Rolland, K. Virbel, J.g Tang, J. H. Zhang. Neuroprotection by Melatonin after Germinal Matrix Hemorrhage in Premature Neonatal Rats. Acta Neurochirurgica Supplemental 2010

A. Manaenko, T. Lekic, Q. Ma, J. H. Zhang, J. Tang. Hydrogen is Neuroprotective after Intracerebral Hemorrhage and Improves Functional Outcomes in Mice. Acta Neurochirurgica Supplemental 2010

N. H. Khatibi, M. Saidi, V. Jadhav, W. Chen, R. Martin, G. Stier, J. Tang, J. H. Zhang. Pretreatment with Granulocyte Colony-stimulating Factor (G-CSF) reduces Cell Death in Mice Subjected to a Surgically Induced Brain Injury. Acta Neurochirurgica Supplemental 2010

N. H. Khatibi, B. Matus, V. Jadhav, W. Chen, R. Martin, G. Stier, J. Tang, J. H. Zhang. Pretreatment with SC-51089, a selective Prostaglandin E2 Antagonist, fails to reduce Brain Edema and Cell Death in Mice subjected to Surgically induced Brain Injury. Acta Neurochirurgica Supplemental 2010

L. Kueppers-Tiedt, A. Manaenko, D. Michalski, A. Guenther, C. Hobohm, A. Wagner, J. H. Zhang, D. Schneider. Combined Systemic Thrombolysis with Alteplase and Early Hyperbaric Oxygen Therapy in Experimental Embolic Stroke in Rats – relationship to Function Outcome and reduction of Structural Damage. Acta Neurochirurgica Supplemental 2010

T. Lekic, A. Manaenko, W. Rolland, K. Virbel, J. Tang, J. H. Zhang. Beneficial Effects of Hyperbaric Oxygen after Neonatal Germinal Matrix Hemorrhage. Acta Neurochirurgica Supplemental 2010

T. Lekic, A. Manaenko, W. Rolland, M. Patterson, J. Tang, J. H. Zhang. Effect of Hydrogen Gas after Germinal Matrix Hemorrhage in Neonatal Rats. Acta Neurochirurgica Supplemental 2010

T. Lekic, A. Manaenko, W. Rolland, J. Tang, J. H. Zhang. The Female Postpartum State worsens Functional Outcomes and Brain Injury after Cerebellar Hemorrhage in Rats. Acta Neurochirurgica Supplemental 2010

N. H. Khatibi, L. K. Lee, Y. Zhou, W. Chen, W. Rolland, R. Martin, R. Applegate, G. Stier, J. H. Zhang. Endothelin Receptor-A Inhibition fails to Attenuate Neonatal Hypoxic-ischemic Brain Injury in Rats. Acta Neurochirurgica Supplemental 2010

H. Suzuki, R. Ayer, T. Sugawara, W. Chen, T. Sozen, Y. Hasegawa, K. Kanamaru and J. H. Zhang. Effects of Recombinant Osteopontin on Blood-brain Barrier Disruption after Subarachnoid Hemorrhage in Rats. Acta Neurochirurgica Supplemental 2010

D. Westra, W. Chen, R. Tsuchiyama, A. Colohan, and J. Zhang. Pretreatment with Normobaric and Hyperbaric Oxygenation worsens Cerebral Edema and Neurologic Outcomes in a Murine Model of Surgically Induced Brain Injury. Acta Neurochirurgica Supplemental 2010

N. Fathali, R. P. Ostrowski, N. H. Khatibi, and J. H. Zhang. The Evolving Landscape of Neuroinflammation after Neonatal Hypoxia-ischemia. Acta Neurochirurgica Supplemental 2010

Editor for Special Journal Issue

J.H. Zhang: Molecular Neurosciences. Neurological Research March 31 (2): 113-209, 2009

Original Article

Q. Hu, C. Chen, J. Yan, X. Yang, X. Shi, J. Zhao, J. Lei, L. Yang, K. Wang, L. Chen, H. Huang, J. Han, J. H. Zhang, C. Zhou. Therapeutic application of gene silencing MMP-9 in a middle cerebral artery occlusion-induced focal ischemia rat model. Experimental Neurology 216: 35-46, 2009

J. Cai, Z. Kang, K. Liu, W. Liu, Y. Li, J. H. Zhang, X. Luo, X. Sun. Neuroprotective Effects of Hydrogen Saline in Neonatal Hypoxia-ischemia Rat Model. Brain Research 1256: 129-137, 2009

A. Manaenko, T. Lekic, T. Sozen, R. Tsuchiyama, J. H. Zhang, and J. Tang. Effect of Gap Junction Inhibition on Intracerebral Hemorrhage-Induced Brain Injury in Mice. Neurological Research 31: 173-178, 2009

I. Solaroglu, J. Cahill, T. Tsubokawa, E. Beskonakli, J. H. Zhang. Granulocyte‐Colony Stimulating Factor protects the brain against experimental stroke via inhibition of apoptosis and inflammation. Neurological Research 31: 167-172, 2009

R. Tsuchiyama, T. Sozen, A. Manaenko, J. H. Zhang, J. Tang. The Effects of Nicotinamide Adenine Dinucleotide on Intracerebral Hemorrhage-Induced Brain Injury in Mice. Neurological Research 31: 179-182, 2009

G. Matchett, N. Fathali, Y. Hasegawa, V. Jadhav, R. Ostrowski, R. Martin, I. Dorotta, X. Sun, J. Zhang. Hydrogen Gas is Ineffective in Moderate and Severe Neonatal Hypoxia-ischemia Rat Models. Brain Research 1259: 90-97, 2009

C. Chen, Q. Hu, J. Yan, X. Yang, X. Shi, J. Lei, L. Chen, Y. Huang, J. Han, J. H. Zhang, C. Zhou. Early inhibition of HIF-1alpha with small interfering RNA reduces ischemic-reperfused brain injury in rats. Neurobiology of Diseases 33: 509-517, 2009

J. Li, W. Zhang, Z. Kang, S. Ding, W. Liu, J. H. Zhang, Y. Guan, and X. Sun. Hyperbaric oxygen preconditioning reduces ischemia-reperfusion injury by inhibition of apoptosis via mitochondrial way in rat brain. Neuroscience 159: 1309-1315, 2009

L. Wang, W. Li, Z. Kang, Y. Liu, X. Deng, W. Xu, H. Tao, R. Li, X. Sun & J.H. Zhang. Hyperbaric Oxygen Preconditioning Attenuates Early Apoptosis after Spinal Cord Ischemia in Rats. J Neurotrauma 26(1): 55-66, 2009

J. Xu, Z. Peng, R. Li, T. Dou, W. Xu, G. Gu, Y. Liu, Z. Kang, H. Tao, J. H. Zhang, R. P. Ostrowski, J. Lu, X. Sun. Normoxic induction of cerebral HIF-1α by acetazolamide in rats: role of acidosis. Neuroscience Letters 451: 374-378, 2009

M. Guerra-Crespo, D. Gleason, A. Sistos, T. Toosky, I. Solaroglu, J.H. Zhang, P. Bryant & J. H. Fallon. Transforming Growth Factor-alpha Induces Neurogenesis and Behavioral Improvement in a Chronic Stroke Model. Neuroscience 160: 470-483, 2009

X. Zheng, Y. Mao, J. Cai, Y. Li, W. Liu, P. Sun, J.H. Zhang, X. Sun, H. Yuan. Hydrogen-Rich Saline Protects against Intestinal Ischemia/Reperfusion Injury in Rats. Free Radical Research 7: 1-7, 2009

Y. Mao, X. Zheng, J. Cai, X. You, X. Deng, J. H. Zhang, L. Jiang, X. Sun. Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. Biochemical and Biophysical Research Communications 381: 602-605, 2009

Y. Zhou, N. Fathali, T. Lekic, J. Tang, J. Zhang. Glibenclamide Improves Neurological Function in Neonatal Hypoxia-ischemia in Rats. Brain Research 1270: 131-9, 2009

T. Sugawara, V. Jadhav, R. Ayer, W. Chen, H. Suzuki, J.H. Zhang. Thrombin Inhibition by Argatroban Ameliorates Early Brain Injury and Improves Neurological Outcomes after Experimental Subarachnoid Hemorrhage in Rat. Stroke 40: 1530-1532, 2009

T. Sozen, R. Tsuchiyama, Y. Hasegawa, H. Suzuki, V. Jadhav, S. Nishizawa, & J. H Zhang. Role of Interleukin-1β in Early Brain Injury after Subarachnoid Hemorrhage in Mice. Stroke 40(7): 2519-2525, 2009

R. Hartman, T. Lekic, H. Rojas, J. Tang, J. Zhang. Assessing functional outcomes following intracerebral hemorrhage in rats. Brain Research 1280: 148-157, 2009

V. Jadhav, R. Ostrowski, W. Tong, B. Matus, R. Jesunathadas, J. H. Zhang. Cyclooxygenase-2 Mediates Hyperbaric Oxygen Preconditioning Induced Neuroprotection in the Mouse Model of Surgical Brain Injury. Stroke 40(9): 3139-3142, 2009

W. Chen, R. Hartman, R. Ayer, S. Marcantonio, J. Kamper, J. Tang, J. H. Zhang. Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain. J Neurochem 111(3): 726-736, 2009

Q. Sun, Z. Kang, J. Cai, W. Liu, Y. Liu, J. H. Zhang, P. Denoble, H. Tao, X. Sun. Hydrogen-rich Saline Protects Myocardium against Ischemic/Reperfusion Injury. Exp Biol Med 234 (10): 1212-1219, 2009

W. Liu, J. Zhang, C. Ma, Y. Liu, R. Li, X. Sun, J. Zhang, W. Xu. Dual effects of hyperbaric oxygen on proliferation and cytotoxicity T lymphocyte activity of rat splenic lymphocyte. Undersea Hyperbaric Medical Journal 36 (3): 155-160, 2009

H. Suzuki, T. Sozen, Y. Hasegawa, W. Chen, J. H. Zhang. Caspase-1 inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice. Stroke 40 (12): 3872-3875, 2009

W. Tong, Wu Chen, R. P. Ostrowski, Q. Ma, R. Souvenir, L. Zhang, J. H. Zhang, J. Tang. Maternal hypoxia increases the activity of MMPs and decreases the expression of TIMPs in the brain of neonatal rats. Developmental Neurobiology 70(3):182-194, 2009

2009 list

Review

J. Cahill, J.H. Zhang. Subarachnoid Hemorrhage: Is It Time for a New Direction? Stroke 40 (3): (26th Princeton Conference Supplement) S86-87, 2009

E. Titova, R. Ostrowski, J.H. Zhang, J. Tang. Experimental Models of SAH for Studies of Cerebral Vasospasm. Neurological Research 31 (6): 568-581, 2009

R. M. Pluta, J. Hansen-Schwartz, J. Dreier, P. Vajkoczy, R. L. Macdonald, S. Nishizawa, H. Kasuya, G. Wellman, E. Keller, A. Zauner, N. Dorsch, J. Clark, S. Ono,  T. Kiris, P. LeRoux, J. H. Zhang. Cerebral Vasospasm following Subarachnoid Hemorrhage: Time for a New World of Thought. Neurological Research 31: 151-158, 2009

G. A. Matchett, M. W. Allard, R. D. Martin, J. H. Zhang. Neuroprotective effect of volatile anesthetic agents: molecular mechanisms. Neurological Research 31: 128-134, 2009

G. A. Matchett, R. D. Martin, J. H. Zhang. Hyperbaric Oxygen Therapy and Cerebral Ischemia: Neuroprotective Mechanisms. Neurological Research 31: 114-121, 2009

R. Ayer, J. Zhang. Connecting Early Brain Injury of Aneurysmal Subarachnoid Hemorrhage to Clinical Practice. Turkish Neurosurgery 2009

T. Wang, I. Solaroglu, J. H. Zhang, X. Qin. Early Brain Injury as a Treatment Target after SAH. Turkish Medical Journal 2009

2009 list

Editorial

I. Solaroglu, J. Zhang. Editorial: The Neurosurgical Role of Epigenome. Surgical Neurology 71: 159-160, 2009

J. Zhang. Introduction to Special Issue: Molecular Neurosciences. Neurological Research 31: 113, 2009

J. Eckermann, J. H. Zhang. Comment: Vertebral artery dissection as an extremely rare cause of spinal epidural hematoma: case report and review of the literature. Acta Neurochirurgia 2009

J. Eckermann, J. H. Zhang. Commentary: High Concentrations of Procoagulant Microparticles in the Cerebrospinal Fluid and Peripheral Blood of Patients with Acute Basal Ganglia Hemorrhage are associated with Poor Outcome. Surgical Neurology 72: 489, 2009

2009 list

Journal Supplement

S. Lee, G. Stier, S. Marcantonio, T. Lekic, M. Allard, R. Martin, J. Zhang. 3% Hypertonic Saline Following Subarachnoid Hemorrhage In Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 102, 2009

S. Lee, V. Jadhav, R. Ayer, T. Lekic, A. Hyong, M. Allard, G. Stier, R. Martin, J. Zhang. Simvastatin Treatment In Surgically Induced Brain Injury In Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 102, 2009

S. Lee, V. Jadhav, R. Ayer, T. Lekic, A. Hyong, G. Stier, R. Martin, J. Zhang. The Antioxidant Effects of Melatonin in Surgically Induced Brain Injury in Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 102, 2009 

V. Jadhav, M. Yamaguchi, A. Obenaus, J. Zhang. MMP Inhibition Attenuates Brain Edema in Surgically-Induced Brain Injury. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 102, 2009

T. Sugawara, V. Jadhav, J. Zhang. Simvastatin Attenuates Cerebral Vasospasm and Improves Outcome by Up-regulation of PI3K/Akt Pathway in a Rat Model of Subarachnoid Hemorrhage. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 102, 2009

W. Chen, V. Jadhav, J. Tang, J. Zhang. HIF-1α Inhibition Ameliorates Neonatal Brain Damage after Hypoxic-ischemic Injury. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 102, 2009

R. E. Ayer, J. Zhang. Melatonin Decreases Mortality Following Subarachnoid Hemorrhage. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 102, 2009

R. Tsuchiyama, T. Sozen, E. Titova, J. H. Zhang, J. Tang,. The Effects of Tetrahydrobiopterin on Intracerebral Hemorrhage – Induced Brain Injury in Mice. The XIV International Symposium Brain Edema and Brain Tissue Injury, June 11-14. 2008. Warsaw, Poland. Acta Neurochirurgica Supplement 106, 155-158, 2009

R. P. Ostrowski, V. Jadhav, W. Chen, J. H. Zhang. Reduced matrix metalloproteinase-9 and cell death after global cerebral ischemia in brains preconditioned with hyperbaric oxygen. The XIV International Symposium Brain Edema and Brain Tissue Injury, June 11-14. 2008. Warsaw, Poland. Acta Neurochirurgica Supplement 106, 47-50, 2009

E. Titova, A. Adami, R. P. Ostrowski, S. Lalas, R. Vlkolinsky, J. H. Zhang, G. A. Nelson, and A. Obenaus. Radiation Exposure Prior to Ischemia Decreases Lesion Volume, Cytotoxic Edema and Cell Death. The XIV International Symposium Brain Edema and Brain Tissue Injury, June 11-14. 2008. Warsaw, Poland. Acta Neurochirurgica Supplement 106, 51-54, 2009

V. Jadhav, R. Ostrowski, W. Tong, B. Matus, C. Chang, J. Zhang. Hyperbaric Oxygen Preconditioning Reduces Postoperative Brain Edema and Improves Neurological Outcomes after Surgical Brain Injury. The XIV International Symposium Brain Edema and Brain Tissue Injury, June 11-14. 2008. Warsaw, Poland. Acta Neurochirurgica Supplement 106, 217-220, 2009

Original Article | Review | Editorial | Journal Supplement | Book Chapter | Book Review

J.H. Zhang: Chinese Neurosurgery Research. Neurological Research, July 2008

J.H. Zhang: Frontiers of Neurosurgery Research. Frontiers in Bioscience, January 2008

Original Article:

R. Ostrowski, G. Graupner, E. Titova, J. Zhang, J. Chiu, N. Dach, D. Corleone, J. Tang, J. Zhang. The Hyperbaric Oxygen Preconditioning-Induced Brain Protection is mediated by A Reduction of Early Apoptosis after Transient Global Cerebral Ischemia. Neurobiology of Disease 29(1): 1-13, 2008

G.J. Gu, Y.P. Li, Z.Y. Peng, J.J. Xu, Z.M. Kang, W.G. Xu, H.Y. Tao, R.P. Ostrowski, J.H. Zhang, X.J. Sun. Mechanism of Ischemic Tolerance induced by Hyperbaric Oxygen Preconditioning involves Up-regulation of Hypoxia-inducible Factor-1alph and Erythropoietin in Rats. J Applied Physiol 104(4): 1185-1191, 2008

R. Ayer, T. Sugawara, W. Chen, W. Tong, J.H. Zhang. Melatonin Decreases Mortality following Severe Subarachnoid Hemorrhage. Journal of Pineal Research March 44(2): 197-204, 2008

Z. Li, W. Liu, Z. Kang, S. Lv, C. Han, L. Yun, X. Sun, J.H. Zhang. Mechanism of Hyperbaric Oxygen Preconditioning in Neonatal Hypoxia-ischemia Rat Model. Brain Research  Feb 27; 1196: 151-156, 2008

S. Zhang, Q. Zhang, J. Zhang, X. Qin. Electro-stimulation of Cerebellar Fastigial Nucleus (FNS) Improves Axonal Regeneration. Front Biosci. 13: 6999-7007, 2008

W. Liu, X. Sun, K, Liu, J.H. Zhang, W. Xu, H. Tao. Repetitive Hyperbaric Oxygen Exposures Enhance Sensitivity to Convulsion by Up-regulation of eNOS and nNOS. Brain Research 1201: 128-134, 2008

T.P. Bravo, G.A. Matchett, V. Jadhav, R.D. Martin, A. Jourdain, A. Colohan, J.H. Zhang, J. Tang. Role of Histamine in Brain Protection in Surgical Brain Injury in Mice. Brain Research 1205: 100-107, 2008

J.S. Li, W.W. Liu, S.J. Ding, W.G. Xu, Y.T. Guan, J.H. Zhang, X.J. Sun. Hyperbaric Oxygen Preconditioning Induces Tolerance against Brain Ischemia-reperfusion Injury by Up-regulation of Antioxidant Enzymes in Rats. Brain Research 1210: 223-229, 2008

Z. Peng, P. Ren, Z.  Kang, J. Du, Q. Lian, Y. Liu, J. H. Zhang, X. Sun. Up-regulated HIF-1α is involved in the Hypoxic Tolerance induced by Hyperbaric Oxygen Preconditioning. Brain Research 30: 1212-1218, 2008 March 27

E. Titova, R. Ostrowski, C. Kevil, W. Tong, H. Rojas, L. Sowers, J.H. Zhang, J. Tang. Reduced Brain Injury in CD18 Deficient Mice after Experimental Intracerebral Hemorrhage. Journal of Neuroscience Research 2008 July 9

A. Hyong, V. Jadhav, S. Lee, W. Tong, J. Rowe, J. H. Zhang, J. Tang. Rosiglitazone, a PPAR Gamma Agonist, Attenuates Inflammation After Surgical Brain Injury in Rodents. Brain Research 1215: 218-224, 2008 April 22

T. Sugawara, R. Ayer, V. Jadhav, W. Chen, T. Tsubokawa, J. H. Zhang. Simvastatin Attenuation of Cerebral Vasospasm after Subarachnoid Hemorrhage in Rats via Increased Phosphorylation of Akt and Endothelial Nitric Oxide Synthase. J Neuroscience Research 2008 Aug 5. [Epub ahead of print]

S. Lee, V. Jadhav, R.E. Ayer, H. Rojas, A. Hyong, T. Lekic, J. Tang, J.H. Zhang. Dual Effects of Melatonin on Oxidative Stress after Surgical Brain Injury in Rats. Journal of Pineal Research 2008 Jun 18

J. Cai, Z. Kang, W. Liu, X. Luo, S. Qiang, J. H. Zhang, S. Ohta, X. Sun, W. Xu, H. Tao, R. Li. Hydrogen Therapy Reduces Apoptosis in Neonatal Hypoxia-ischemia Rat Model. Neuroscience Letters 441(2): 167-172, 2008

W. Tang, Z. Chen, Z. Liu, J. Zhang, G. Xi, H. Feng. The Effect of Ecdysterone on Cerebral Vasospasm following Experimental Subarachnoid Hemorrhage in Vitro and in Vivo. Neurological Research 30: 571-580, 2008

W. Chen, V. Jadhav, J. Tang, J. H. Zhang. HIF-1α Inhibition Ameliorates Neonatal Brain Injury in a Rat Pup Hypoxic-ischemic Model. Neurobiology of Disease

P. Ren, Z. Kang, X. Sun, G. Gu, Y. Liu, W. Xu, H. Tao, J.H. Zhang, H. Li. Hyperbaric Oxygen Preconditioning Promotes Angiogenesis in Rat Liver after Partial Hepatectomy. Life Science 83, 236-241, August 2008

V. Jadhav, T. Sugawara, J. Zhang, P. Jacobson, A. Obenaus. Magnetic Resonance Imaging Detects and Predicts Early Brain Injury after Subarachnoid Hemorrhage in a Canine Experimental Model. J Neurotrauma 2008 Sep;25(9):1099-1106.

C. Han, L. Lin, W. Zhang, L. Zhang, S. Lv, Q. Sun, H. Tao, J. H. Zhang, X. Sun. Hyperbaric Oxygen Preconditioning Alleviates Myocardial Ischemic Injury in Rats. Experimental Biology and Medicine

T. Sugawara, V. Jadhav, R. Ayer, W. Chen, H. Suzuki, J.H. Zhang. Thrombin Inhibition by Argatroban Ameliorates Early Brain Injury and Improves Neurological Outcomes after Experimental Subarachnoid Hemorrhage in Rat. Stroke 2008

L. Wang, W. Li, Z. Kang, Y. Liu, X. Deng, H. Tao, W. Xu, R. Li, X. Sun, J. Zhang. Hyperbaric Oxygen Preconditioning attenuates Early Apoptosis after Spinal Cord Ischemia in Rats. J Neurotrauma

2008 list

Review

V. Jadhav, J. Zhang. Surgical Brain Injury: Prevention is better than Cure. Front Biosci 13: 3793-3797, 2008

S. Zhang, Q. Zhang, J.H. Zhang, X. Qin. NgR Acts as an Inhibitor to Axonal Regeneration in Adults. Front Biosci 13: 2030-2040. 2008

T. Lekic, J.H. Zhang. Posterior Circulation Stroke and Animal Models. Front Biosci 13: 1827-1844, 2008

Nishizawa S, Zhang JH. Basic Research and Treatment for Cerebral Vasospasm after Subarachnoid Hemorrhage: the Present and Future Prospects. No Shinkei Geka. 2008 Feb;36(2):121-33.

J. Cahill, J. H. Zhang. Pre-Vasospasm: Early Brain Injury (Review). Acta Neurochirurgica Supplement 104, pp-7-10, 2008

R.E. Ayer, J.H. Zhang. Oxidative Stress in SAH: Significance in Acute Brain Injury and Vasospasm. Acta Neurochirurgica Supplement 104, pp33-42, 2008

T. Sugawara, R. Ayer, J.H. Zhang. Role of Statins in Cerebral Vasospasm. Acta Neurochirurgica Supplement 104, pp287-290, 2008

S. Armin, A. Colohan, J. H. Zhang. Vasospasm in Traumatic Brain Injury (Review). Acta Neurochirurgica Supplement 104, pp421-426, 2008

J. Cahill, J.H. Zhang. The Central Role of Early Brain Injury after SAH. Stroke (Princeton Conference Special Issue) 2008

W. Chen, R.P. Ostrowski, A. Obenaus, J.H. Zhang. Pro-death or Pro-survival: Two Facets of Hypoxia Inducible Factor-1 in Perinatal Brain Injury. Experimental Neurology 2008

2008 list

Editorial

T. Kiris, J. Zhang. Preface: Cerebral Vasospasm New Strategies for Research and Treatment. Acta Neurochirurgica Supplement 104, pp-V-VI. Springer, 2008

J. Zhang. Chinese Neurosurgery Research. Neurological Research 30(6): 549, July 2008

Y. Zhang, J. Zhang. Dr. Chong-cheng Wang and Beijing Neurosurgical Institute. Neurological Research 30(6): 550-551, July 2008

J. Zhang. Editor’s Remark: Hyperbaric Oxygen for Neurological Diseases. Ed: J.H. Zhang. Best Publishing 2008

J. Chen, X. Xu, J. Xu, J. Zhang. Preface. Animal Models of Acute Neurological Injury. Ed: J. Chen, X. Xu, J. Xu, J. Zhang. Humana 2008

J. Zhang. Preface: Advancements in Neurological Research. Ed: J. Zhang. Research Signpost 2008

J. Zhang. Comment: Microelectrode Findings and Topographic Reorganization ….. Acta Neurochirurgica 2008

J. Zhang. Comment: RNA Interference Targeting EphA2 inhibits Proliferation, induces Apoptosis and Cooperates with Cytotoxic Drugs in Human Glioma Cells. Surgical Neurology 2008

R. Ostrowski, J. Zhang. Comment: Risk Factors for Short-Term Mortality from Carbon Monoxide Poisoning Treated with Hyperbaric Oxygen. Critical Care Medicine 36(9): 2684-2685, 2008

I. Solaroglu, J. Zhang. Editorial: The Neurosurgical Role of Epigenome. Surgical Neurology 2008

X. Sun, J.H. Zhang. Hydrogen should be an Endogenous Antioxidant in the Body. Academic Report of the Second Military Medical University 29 (3), 2008

2008 list

Journal Supplement

J.H. Zhang. Subarachnoid Hemorrhage: What is New and What is Next? Other Meeting and Journal Issues. Chinese Journal of Non-Invasive Neurosurgery 13: 2-3, March 2008

J. Cahill, I. Solaroglu, J.H. Zhang. Apoptotic Markers in Vasospasm after Experimental SAH. Acta Neurochirurgica Supplement 104, pp11-16, 2008

W. Shi, L. Huang, R. Wang, J. Sun, F. Wang, C. Liu, L. Zhou, J.H. Zhang. Time Course of Oxyhemoglobin Induces Apoptosis in Mice Brain Cells In Vivo. Acta Neurochirurgica Supplement 104, pp23-26, 2008

H. Yatsushige, M. Yamaguchi-Okada, C. Zhou, J.W. Calvert, J. Cahill, A.R.T. Colohan, J.H. Zhang. Inhibition of c-Jun N-terminal Kinase Pathway Attenuates Cerebral Vasospasm after Experimental SAH through the Suppression of Apoptosis. Acta Neurochirurgica Supplement 104, pp27-32, 2008

Z. Chen, G. Zhu, J.H. Zhang, Z. Liu, W. Tang, H. Feng. Ecdysterone-sensitive Smooth Muscle Cell Proliferation Stimulated by Conditioned Medium of Endothelial Cells Cultured with Bloody CSF. Acta Neurochirurgica Supplement 104, pp183-188, 2008

W. Tang, G. Zhu, J. Zhang, Z. Chen, Z. Liu, H. Feng. The Effect of Oxyhemoglobin on the Proliferation and Migration of Cultured Vascular Advential Fibroblast. Acta Neurochirurgica Supplement 104, pp189-196, 2008

W. Tang, G. Zhu, J. Zhang, Z. Chen, Z. Liu, H. Feng. The Effect of Oxyhemoglobin on the Proliferation and Migration of Cultured Vascular Smooth Muscle Cells. Acta Neurochirurgica Supplement 104, pp197-202, 2008

T. Sugawara, A. Wang, V. Jadhav, T. Tsubokawa, A. Obenaus, & J.H. Zhang. MRI in the Canine Double-Hemorrhage SAH Model. Acta Neurochirurgica Supplement 104, pp235-239, 2008

Z. Liu, G. Zhu, J. Zhang, Z. Chen, W. Tang, X. Wang, H. Feng. Ecdysterone Attenuates Vasospasm following Experimental SAH in Rabbits. Acta Neurochirurgica Supplement 104, pp297-304, 2008

S. Lee, G. Stier, S. Marcantonio, T. Lekic, M. Allard, R. Martin, J. Zhang. 3% Hypertonic Saline Following Subarachnoid Hemorrhage In Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

S. Lee, V. Jadhav, R. Ayer, T. Lekic, A. Hyong, M. Allard, G. Stier, R. Martin, J. Zhang. Simvastatin Treatment In Surgically Induced Brain Injury In Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

S. Lee, V. Jadhav, R. Ayer, T. Lekic, A. Hyong, G. Stier, R. Martin, J. Zhang. The Antioxidant Effects of Melatonin in Surgically Induced Brain Injury in Rats. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008 

V. Jadhav, M. Yamaguchi, A. Obenaus, J. Zhang. MMP Inhibition Attenuates Brain Edema in Surgically-Induced Brain Injury. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

T. Sugawara, V. Jadhav, J. Zhang. Simvastatin Attenuates Cerebral Vasospasm and Improves Outcome by Up-regulation of PI3K/Akt Pathway in a Rat Model of Subarachnoid Hemorrhage. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

W. Chen, V. Jadhav, J. Tang, J. Zhang. HIF-1α Inhibition Ameliorates Neonatal Brain Damage after Hypoxic-ischemic Injury. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

R. E. Ayer, J. Zhang. Melatonin Decreases Mortality Following Subarachnoid Hemorrhage. Intracranial Pressure and Brain Monitoring Conference (ICP2007). Acta Neurochirurgica Supplement 2008

E. Titova, R. Ostrowski, J. Rowe, W. Chen, J.H. Zhang, J. Tang. Effects of Superoxide Dismutase and Catalase Derivates on Intracerebral Hemorrhage-induced Brain Injury in Rats. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

E. Titova, C. Kevil, R. Ostrowski, H. Rojas, S. Liu, J. Zhang, J. Tang. Deficiency of CD 18 Gene Reduces Brain Edema in Experimental Intracerebral Hemorrhage in Mice. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

E. Titova, R.P. Ostrowski, J.H. Zhang, J. Tang. Effects of Amantadine Sulphate on Intracerebral Hemorrhage-induced Brain Injury in Rats. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

T. Lekic, J. Tang, J. Zhang. Rat Model of Intra-cerebellar Hemorrhage. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

T. Lekic, H. Rojas, J. Tang, J. Zhang. A Rat Model of Pontine Hemorrhage. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

H. A. Rojas, R. Ayer, W. Chen, S. Lee, V. Jadhav, E. Titova, R. Martin, R. Hartman, J. Tang, J. Zhang. Long Term Effects of Melatonin after Intracerebral Hemorrhage in Rats. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

H. A. Rojas, T. Lekic, W. Chen, V. Jadhav, E. Titova, R. Martin, J. Tang, J. Zhang. The Antioxidant Effects of Melatonin after Intracerebral Hemorrhage in Rats. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

R. Hartman, H. Rojas, J. Zhang. Longitudinal Behavioral Characterization of a Rat Model of ICH. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

R.E. Ayer, J.H. Zhang. The Clinical Significance of Acute Brain Injury in Subarachnoid Hemorrhage and Opportunity for Intervention. The 2nd International Conference on ICH. Acta Neurochirurgica Supplement 105, 2008

2008 list

Book Chapter

H. Rojas, J.H. Zhang. Animal Models of Spontaneous Intracerebral Hemorrhage. Advancements in Neurological Research. Ed: J.H. Zhang. Research SignPost 37/661 (2): 39-89, 2008

J. Cahill, J. Zhang. Early Brain Injury and the Role of Apoptosis after a Subarachnoid Hemorrhage. Advancements in Neurological Research. Ed: J.H. Zhang. Research SignPost 37/661 (2): 91-119, 2008

G.A. Matchett, R. Martin, J. Zhang. Hyperbaric Oxygen Therapy and Cerebral Ischemia. Advancements in Neurological Research. Ed: J.H. Zhang. Research SignPost 37/661 (2): 229-249, 2008

G. A. Matchett, C. Higuchi, M. Allard, R. Martin, J. Zhang. Volatile Anesthetics and Cerebral Ischemia: Neuroprotective Mechanisms, Clinical Implications. Advancements in Neurological Research. Ed: J.H. Zhang. Research SignPost 37/661 (2): 251-274, 2008

R. P. Ostrowski, J. Zhang. Mechanisms of Hyperbaric Oxygen in Neurological Disorders. Hyperbaric Oxygen for Neurological Disorders. Ed: J.H. Zhang. Pp85-114, Best Publishing 2008

P. Ren, X.J. Sun, J. H. Zhang. Hyperbaric Oxygen for Carbon Monoxide Poisoning. Hyperbaric Oxygen for Neurological Disorders. Ed: J.H. Zhang. Pp345-374, Best Publishing 2008

J. Cahill, J. Zhang. Brain Monitoring. Animal Models of Acute Neurological Injury. Ed: J. Chen, X. Xu, J. Xu, J. Zhang. Humana 2008

R. Ayer, J. Cahill, T. Sugawara, V. Jadhav, J. Zhang. Rodent Surgical Procedures and Tissue Collection. Animal Models of Acute Neurological Injury. Ed: J. Chen, X. Xu, J. Xu, J. Zhang. Humana 2008

J. Cahill, J. Zhang. Monofilament Puncture Perforation Subarachnoid Hemorrhage Rat Model. Animal Models of Acute Neurological Injury. Ed: J. Chen, X. Xu, J. Xu, J. Zhang. Humana 2008

2008 list

Book Review

Y. Zhou, J.H. Zhang. THE PSEUDOTUMOR CEREBRI SYNDROME by Ian Johnston, Brain Owler and John Pickard, published by Cambridge University Press, New York, 2007, 356 pp. Price: $160.00. In Journal of Neuropathology and Experimental Neurology, October - November 2008

Editor for Special Journal Issue | Original Article | Review | Editorial |  Book Chapter

Editor for Special Journal Issue

J.H. Zhang: Hyperbaric Oxygen on Neurological Disorders. Neurological Research 29 (2) March 2007

Original Article

J. Cahill, J. Calvert, S. Marcantonio & J. Zhang. P53 May Play an Orchestrating Role in Apoptotic Cell Death after Experimental SAH. Neurosurgery 60: 531-545, 2007 http://dx.doi.org/10.1227/01.NEU.0000249287.99878.9B

V. Jadhav, I. Solaroglu, A. Obenaus, J. H. Zhang. Neuroprotection against Surgically Induced Brain Injury. Surgical Neurology 67:15-20, 2007 http://dx.doi.org/10.1016/j.surneu.2006.07.014

V. Jadhav, G. Matchett, F. P. Hsu & J.H. Zhang. Inhibition of Src tyrosine kinase and effect on outcomes in a new in vivo model of surgically induced brain injury. J Neurosurg. 2007 Apr;106(4):680-6.

J. Calvert & J. Zhang. Oxygen Treatment Restores Energy Status following Experimental Neonatal Hypoxia-Ischemia. Pediatric Critical Care Med 8: 165-173, January 2007 http://dx.doi.org/10.1097/01.PCC.0000257113.75488.84

T. Tsubokawa, V. Jadhav, I. Solaroglu, Y. Shiokawa, Y. Konishi & J. Zhang. Lecithinized Superoxide Dismutase Attenuates Focal Cerebral Ischemic Injury via Anti-apoptotic Mechanisms in Rats. Stroke 38: 1057-1062, February 2007 http://dx.doi.org/10.1161/01.STR.0000257978.70312.1d

G. Matchett, J. Calinisan, G. Matchett, R. Martin & J. Zhang. The Effect of Granulocyte-colony Stimulating Factor in Global Cerebral Ischemia in Rats. Brain Research 1136: 200-207, 2007 http://dx.doi.org/10.1016/j.brainres.2006.12.023

W. Lo, T. Brava, V. Jadhav, J. Zhang, J. Tang. NADPH Oxidase Inhibition Improves Neurological Outcomes in Surgically-induced Brain Injury. Neuroscience Lett 414: 228-232, 2007 http://dx.doi.org/10.1016/j.neulet.2006.12.055

H. Yatsushige, R. Ostrowski, T. Tsubokawa, A. Colohan, J.H. Zhang. Role of c-Jun N-terminal Kinase in Early Brain Injury after SAH. J Neurosci Res 85: 1436-1448, 2007 http://dx.doi.org/10.1002/jnr.21281

K. Yata, G. Matchett, T. Tsubokawa, J. Tang, K.Kanamaru & J.H. Zhang. Granulocyte-colony Stimulating Factor Inhibits Apoptotic Neuron Loss after Neonatal Hypoxia-Ischemia in Rats. Brain Research 1145: 227-238, 2007 http://dx.doi.org/10.1016/j.brainres.2007.01.144

Z. Huang, Z. Kang, G. Gu, G. Peng, Y. Liu, H. Tao, W. Xu, J.H. Zhang, X. Sun. Therapeutic Effects of Hyperbaric Oxygen in a Rat Model of Endothelin-1 Induced Focal Cerebral Ischemia. Brain Research 1153: 204-213, 2007 http://dx.doi.org/10.1016/j.brainres.2007.03.061

E. Titova, R.P. Ostrowski, L.C. Sowers, J.H. Zhang, J. Tang. Effects of Apocynin and Ethanol on Intracerebral Hemorrhage-Induced Brain Injury in Rats. Clin Exp Pharmacol Physiol 34(9): 845-850, 2007

D. Zhou, G. Matchett, V. Jadhav, N. Dach & J. Zhang. The Effect of 2-Methoxyestradiol, a HIF-1α Inhibitor, in Global Cerebral Ischemia in Rats. Neurological Research Aug 22, 30(3): 268-271, 2007

S. Liu, J. Tang, R. Ostrowski, E. Titova, C. Monroe, W. Chen, W. Lo, R. Martin, J. Zhang. Oxidative Stress after SAH in gp91phox Knockout Mice. Can J Neurol Sci 34(3): 356-361, 2007

M. Yamaguchi, V. Jadhav, A. Obenaus, A. Colohan & J. Zhang. Matrix Metalloproteinase Inhibition Attenuates Brain Edema in an in vivo Model of Surgically-Induced Brain Injury. Neurosurgery 61(5): 1067-1075, 2007

T. Sugawara, R. Ayer, V. Jadhav, J. H. Zhang. A New Grading System Evaluating Bleeding Scale in Filament Perforation Subarachnoid Hemorrhage Rat Model. J Neurosci Methods 167(2): 327-334, Aug 12, 2007

2007 list

Review

R. L. Macdonald, R. Pluta, and J. H. Zhang. Cerebral Vasospasm after Subarachnoid Hemorrhage: The Emerging Revolution. Nature Clinical Practice Neurology 3(5): 256-263, 2007 http://dx.doi.org/10.1038/ncpneuro0490

J. Hansen-Schwartz, P. Vajkoczy, R. L. Macdonald, R. M. Pluta, J. H. Zhang. Cerebral Vasospasm: Looking beyond vasoconstriction. TiPS 28(6): 252-256, 2007 http://dx.doi.org/10.1016/j.tips.2007.04.002

I. Solaroglu, V. Jadhav, J.H. Zhang. Neuroprotective Effect of Granulocyte-colony Stimulating Factor (Review). Frontiers in Biosciences 12: 712-724, 2007 http://dx.doi.org/10.2741/2095

J. W. Calvert, J.H. Zhang. HBO and Brain Physiology (Review). Neurological Research 2007 29: 132-141, 2007

2007 list

Editorial

R. Ayer, J.H. Zhang. Comment on: Neural Stem Cell Markers, Nestin and Musashi Proteins, in Progression of Human Glioma: Correlation of Nestin with Prognosis of Patient Survival. Surgical Neurology 68: 143-144, 2007

J.H. Zhang. Introduction to Special Issue: Hyperbaric Oxygen on Neurological Diseases. Neurological Research 29: 113-115, 2007

J. Hansen-Schwartz & J.H. Zhang. Cerebral Vasospasm Revisited - A Conference Where East Meets West. International Journal of Stroke 2: 2-3, 2007 http://dx.doi.org/10.1111/j.1747-4949.2007.00082.x

2007 list

Book Chapter

R. Ostrowski, A. Colohan, J. Zhang. Molecular Signaling Pathways in Early Brain Injury after SAH. Ed P. Chan, Hand Book of Neurochemistry and Molecular Neurobiology - Acute Ischemic Injury and Repair in the Nervous System. Pp235-253, 2007

Editor for Special Journal Issue | Original Article | Review | Editorial/Letter/Comment | Journal Supplement

Editor for Special Journal Issue

J.H. Zhang: Subarachnoid Hemorrhage. Neurological Research 28 (4): 2006

J.H. Zhang: Cerebral Vasospasm. Neurological Research 28 (7): 2006

Original Article

R. Ostrowski, J. Tang & J.H. Zhang. HBO Suppresses NADPH Oxidase in a Rat SAH Model. Stroke 37: 1314-1318, 2006 http://dx.doi.org/10.1161/01.STR.0000217310.88450.c3

N. Shimamura, H. Yatsushige, G. Matchett, J. Calvert, H. Ohkuma & J.H. Zhang. Inhibition Of Integrin Αvβ3 Ameliorates Focal Cerebral Ischemic Damage In The Rat Middle Cerebral Artery Occlusion Model. Stroke 37: 1902-1909, 2006 http://dx.doi.org/10.1161/01.STR.0000226991.27540.f2

N. Shimamura, G. Matchett, T. Tsubokawa, H. Ohkuma, J.H. Zhang. Comparison of Silicon-coated Nylon Suture to Plain Nylon Suture in the Rat Middle Cerebral Artery Occlusion Model. J Neurosci Methods. 156: 161-165, 2006 http://dx.doi.org/10.1016/j.jneumeth.2006.02.017

J. Cahill, J. Calvert, I. Solaroglu & J.H. Zhang. Vasospasm and p53 Induced Apoptosis in an Experimental Model of Subarachnoid Hemorrhage. Stroke 37: 1868-1874, 2006 http://dx.doi.org/10.1161/01.STR.0000226995.27230.96

T. Tsubokawa, I. Solaroglu, H. Yatsushige, J. Cahill, K. Yata & J.H. Zhang. Cathepsin and Calpain Inhibitor E64d Attenuates Matrix Metaloprotease-9 Activity after Focal Cerebral Ischemia. Stroke 37: 1888-1894, 2006 http://dx.doi.org/10.1161/01.STR.0000227259.15506.24

J. Tang, I. Kusaka, A. Massey, S. Rollins, J.H. Zhang. Increased RhoA Translocation in Aorta of Diabetic Rats. Acta Pharmacologica Sinica 27: 543-548, 2006 http://dx.doi.org/10.1111/j.1745-7254.2006.00325.x

W. Shi, L. Huang, S. Wang, J. Sun, F. Wang, Z. Liu, L. Zhou, J.H. Zhang. OxyHb Produces Neuronal Apoptosis after SAH. Chinese J Neurosurg 22: 257-258, 2006

T. Tsubokawa, M. Yamaguchi-Okada, J. Calvert, I. Solaroglu, N. Shimamura, K. Yata & J. H. Zhang. Neurovascular and Neuronal Protection by E64d after Focal Cerebral Ischemia in Rats. J Neurosci Res 84: 832-840, 2006 http://dx.doi.org/10.1002/jnr.20977

J. Calvert, J. Cahill, M. Yamaguchi-Okada, J.H. Zhang. Oxygen Treatment Following Experimental Hypoxia-Ischemia alters the Expression of HIF-1alpha and its Downstream Target Genes. J Appl Physiol. 101: 853-865, 2006 http://dx.doi.org/10.1152/japplphysiol.00268.2006

G. Matchett, J. Hahn, A. Obenaus, J.H Zhang. Surgically Induced Brain Injury in Rats: Effect of EPO. J Neuroscience Method 158: 234-241, 2006 http://dx.doi.org/10.1016/j.jneumeth.2006.06.003

G. Miao, R. Ostrowski, J. Mace,, A. Hopper, R. Peverini, R. Chinnock, J.H, Zhang, E. Hathout. Dynamic Production of Hypoxia-Inducible Factor-1α in Early Transplanted Islets. Am J Transplantation 6: 2636-2643, 2006 http://dx.doi.org/10.1111/j.1600-6143.2006.01541.x

H. Yatsushige, J. Calvert, J. Cahill & J.H. Zhang. Limited Role of Inducible Nitric Oxide Synthase in Brain Barrier Function following Experimental Subarachnoid Hemorrhage. J Neurotrauma 23: 1874-1882, 2006 http://dx.doi.org/10.1089/neu.2006.23.1874

N. Shimamura, G. Matchett, I. Solaroglu, T. Tsubokawa1, H. Ohkuma, J. H. Zhang. Inhibition of integrin alphavbeta3 reduces blood-brain barrier breakdown in focal ischemia in rats. J Neurosci Res. 2006 Dec;84(8):1837-47. http://dx.doi.org/10.1002/jnr.21073

I. Solaroglu, T. Tsubokawa, J. Cahill & J.H. Zhang. Anti-apoptosis Effect of Granulocyte-colony Stimulating Factor after Focal Cerebral Ischemia in Rats. Neuroscience (cover art) 143: 965-974, 2006 http://dx.doi.org/10.1016/j.neuroscience.2006.09.014

2006 list

Review

J. Cahill, J. Calvert, J.H. Zhang. Mechanisms of Early Brain Injury after Subarachnoid Hemorrhage (Review). J Cereb Blood Flow Met 26: 1341-1353, 2006 http://dx.doi.org/10.1038/sj.jcbfm.9600283

I. Solaroglu, J. Cahill, V. Jadhav, J.H. Zhang. A Novel Neuroprotectant Granulocyte-colony Stimulating Factor (Review). Stroke 37: 1123-1128, 2006 http://dx.doi.org/10.1161/01.STR.0000208205.26253.96

R. Ostrowski, A. Colohan, J.H. Zhang. Molecular Signaling Pathways in Early Brain Injury after SAH (Review). Neurological Research 28: 399-414, 2006

S. Armin, A. Colohan, J.H. Zhang. Traumatic Subarachnoid Hemorrhage: Our Current Understanding and its Evolution over the Past Half Century (Review). Neurological Research 28: 445-452, 2006 http://dx.doi.org/10.1179/016164106X115053

2006 list

Editorial/Letter/Comment

J. H. Zhang. Introduction to Special Issue: Subarachnoid Hemorrhage. Neurological Research 28: 369-371, 2006

I. Solaroglu, J. Cahill, V. Jadhav, J.H. Zhang. Response to Letter by Schabitz et al. Stroke 37: 1655, 2006 http://dx.doi.org/10.1161/01.STR.0000227378.20245.df

J.H. Zhang. Introduction to Special Issue: Cerebral Vasospasm. Neurological Research 28: 687-689, 2006

J.H. Zhang. Pravastatin Prevents Ischemia-reperfusion Injury in Rat Sciatic Nerve. Comment. Surgical Neurology 66: 338-339, 2006

2006 list

Journal Supplement

R.P. Ostrowski, A.R.T. Colohan, J.H. Zhang. Neuroprotective Effect of Hyperbaric Oxygen in a Rat Model of Subarachnoid Hemorrhage. Acta Neurochirugica Supplement 96: 188-193, 2006

Editor for Special Journal Issue | Original Article | Review | Editorial | Journal Supplement | Book Review

Editor for Special Journal Issue

J.H. Zhang: Cerebral Vascular Diseases. Pathophysiology 12: 2005

J.H. Zhang: Experimental Therapies for Stroke. Neurological Research 2005 27 (3): 2005

Original Article

Y. Li, C. Zhou, J. W. Calvert, A. Colohan, J. Zhang. Multiple Effects of HBO on HIF1alpha Expression and Apoptotic Genes in Global Ischemia Rat Model. Experimental Neurology 191: 198-210, 2005 http://dx.doi.org/10.1016/j.expneurol.2004.08.036

C. Smelley, R.D. Specian, J. Tang, J. Zhang. Gastric Ulcer after Intracranial Hemorrhage in Rats. Brain Res 1038: 198-207, 2005 http://dx.doi.org/10.1016/j.brainres.2005.01.042

M. Shaya, A. Dubey, C. Berk, E. Gonzalez-Toledo, J.H. Zhang, G. Caldito, A. Nanda. Factors Influencing Outcome in Intracerebral Hematoma: a Simple, Reliable, and Accurate method to Grade Intracerebral Hemorrhage. Surgical Neurology 63: 343-348, 2005 http://dx.doi.org/10.1016/j.surneu.2004.06.019

D. Yin, N. Tamaki, A. Parent & J. Zhang. Insulin-like Growth Factor-I Decreased Etoposide-induced Apoptosis in Glioma Cells by increasing BCl-2 Expression and Decreasing CPP32 Activity. Neurological Research 27: 27-35, 2005 http://dx.doi.org/10.1179/016164105X18151

D. Yin, J. Zhang. Delayed and Multiple Hyperbaric Oxygen Treatments Expand Therapeutic Window in Focal Cerebral Ischemia Model. NeuroCritical Care 2: 206-211, 2005 http://dx.doi.org/10.1385/NCC:2:2:206

G. Mychaskiw, J. Pan, S. Shah, A. Zubkov, B. Clower, A. Badr & J.H. Zhang. Effects of hyperbaric oxygen on skin blood flow and tissue morphology following sciatic nerve constriction. Pain Physician. 2005 Apr;8(2):157-61.

R. Ostrowski, A. Colohan & J. Zhang. Mechanisms of Hyperbaric Oxygen Induced Neuroprotection in a Rat model of Subarachnoid Hemorrhage. J Cereb Blood Flow Metab 25: 554-571, 2005 http://dx.doi.org/10.1038/sj.jcbfm.9600048

C. Zhou, M. Yamaguchi, A. Colohan, J. Zhang. Role of p53 and apoptosis in cerebral vasospasm after experimental subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2005 May;25(5):572-82. http://dx.doi.org/10.1038/sj.jcbfm.9600069

R.V. Patwardhan, W. Besio, J.W. Calvert, G. Kusaka, I. Kusaka, J. Zhang, A. Nanda. Electroconvulsive Therapy for Seizure Control: Preliminary Data in a New Seizure Generation and Control Model. Front Biosci 10: 3013-3019, 2005 http://dx.doi.org/10.2741/1758

R.V. Patwardhan, W. Besio, J.W. Calvert, G. Kusaka, I. Kusaka, J. Zhang, A. Nanda. Technical Note: Preliminary Results in Development of a Novel Intracisternal Penicillin Seizure Model in the Rat. Front Biosci 10: 3009-3012, 2005 http://dx.doi.org/10.2741/1757

Y. Sun, J. Calvert, J. Zhang. Neonatal hypoxia/ischemia is Associated with Decreased Inflammatory Mediators after Erythropoietin Administration. Stroke. 2005 Aug;36(8):1672-8. Epub 2005 Jul 21. http://dx.doi.org/10.1161/01.STR.0000173406.04891.8c

H. Yatsushige, M. Yamaguchi, J. Calvert, C. Zhou & J. Zhang. Role of JNK in Cerebral Vasospasm after Experimental Subarachnoid Hemorrhage. Stroke 36: 1538-1543, 2005 http://dx.doi.org/10.1161/01.STR.0000170713.22011.c8

M. Yamaguchi, J. Calvert, G. Kusaka & J. Zhang. One-stage anterior approach for four-vessel occlusion in rat. Stroke. 2005 Oct;36(10):2212-4. Epub 2005 Sep 15. http://dx.doi.org/10.1161/01.STR.0000182238.08510.c5

J. Tang, J. Liu, C. Zhou, D. Ostanin, M. Grisham, D.N. Granger & J. Zhang. Role of NADPH oxidase in the brain injury of intracerebral hemorrhage. J Neurochem. 2005 Sep;94(5):1342-50. Epub 2005 Jul 11. http://dx.doi.org/10.1111/j.1471-4159.2005.03292.x

2005 list

Review

J.W. Calvert & J.H. Zhang. Pathophysiology of Hypoxia-Ischemia Insult during Perinatal Period. Neurological Research 27: 246-260, 2005 http://dx.doi.org/10.1179/016164105X25216

J. Zhang, T. Lo, G. Mychaskiw, A. Colohan. Mechanisms of Hyperbaric Oxygen and Neuroprotection in Stroke. Pathophysiology 12: 63-78, 2005 http://dx.doi.org/10.1016/j.pathophys.2005.01.003

2005 list

Editorial

J.H. Zhang. Introduction to Special Issue: Experimental Therapies for Stroke. Neurological Research 2005 27: 227-228, 2005

J. Zhang. Introduction to Special Issue: Cerebral Vascular Diseases. Pathophysiology 12: 3-4, 2005

2005 list

Journal Supplement

Y. Dai, J. Tang & J. Zhang. Role of Cl- in Cerebral Vascular Tone and Expression of Na+-K+-2Cl- Co-transporter after Neonatal Hypoxia-ischemia. Canadian Journal of Physiology & Pharmacology Supplemental 83: 767-773, 2005

J. Tang, S. Fitzgerald, B. Boughtman, S. Cole, M. Brands & J.H. Zhang. Decreased RhoA Expression in Myocardium of Diabetic Rats. Canadian Journal of Physiology & Pharmacology Supplemental 83: 775-783, 2005

2005 list

Book Review

J. Cahill J. Zhang. Book Review: Mechanisms of Secondary Brain Damage From Trauma and Ischemia: Recent Advances of Our Understanding. (Acta Neurochirurgica Supplement 89. A. Baethmann, J. Eriskat, J. Lehmberg and N. Plesnila, editors. New York: Springer Wien New York. 2004. 127 pp, illus. ISBN 3-211-20932-8. Price: $129.00.) J Neurosurg 102: 581, 2005

R. Ostrowski J. Zhang. Microelectrode Recording in Movement Surgery. Zvi Israel and Kim J. Burchiel, editors. New York: Thiemes, 2004. 220 pp, illus. ISBN 1-58890-172-4. Price: $149.00. J Neurosurg 102: 755-756, 2005

J. Calver J. Zhang. Textbook of Hyperbaric Medicine, 4th Revised and Expanded Edition. K.K. Jain. Cambridge: Hogrefe Huber, 2004, 536 pp, illus. ISBN 0-88937-277-2. Price $139.00. J Neurosurg 102: 958, 2005

Editor for Special Journal Issue | Original Article | Review | Editorial | Journal Supplement | Book Chapter | Book Review

Editor for Special Journal Issue

J.H. Zhang: Apoptosis in Cerebral Ischemia. Neurological Research 26 (8): 2004

Original Article

Y. Miyagi & J. Zhang. α, β-Methylene ATP Enhances P2Y4-contraction of Rabbit Basilar Artery. Am J Physiol Heart & Circulatory Physiol 286: H1546-1551, 2004 http://dx.doi.org/10.1152/ajpheart.00926.2003

Y. Sun, C. Zhou, A. Nanda, J. Zhang. Mechanism of Erythropoietin-induced Neuroprotection in Neonatal Hypoxia. J Cereb Blood Flow Metab 24: 259-270, 2004 http://dx.doi.org/10.1097/01.WCB.0000110049.43905.AC

M. Ishikawa, K. Stokes, J.H. Zhang, A. Nanda, D.N. Granger. Cerebral Microvascular Responses to Hypercholesterolemia: Roles of NADPH Oxidase and P-selectin. Circ Res 94: 239-244, 2004 http://dx.doi.org/10.1161/01.RES.0000111524.05779.60

C. Zhou, M. Yamaguchi, G. Kusaka, C. Schonholz, A. Nanda, J. Zhang. Caspase Inhibitor Prevents Endothelial Apoptosis and Cerebral Vasospasm. J Cereb Blood Flow Metab 24: 419-431, 2004 http://dx.doi.org/10.1097/00004647-200404000-00007

G. Kusaka, J.W. Calvert, C. Smelley, A. Nanda, J. Zhang. A New Lumbar Method for Monitoring Cerebrospinal Fluid Pressure in Rats. J Neurosci Methods 135: 121-127, 2004 http://dx.doi.org/10.1016/j.jneumeth.2003.12.013

A. Jawahar, F. Ampil, C. Weilbaecher, G. Hartman, J. Zhang, A. Nanda. Management Strategies for Patients with Brain Metastases: Has Radiosurgery Made a Difference? South Med J 97: 254-258, 2004 http://dx.doi.org/10.1097/01.SMJ.0000060569.47897.75

A. Jawahar, R. Matthew, A. Minagar, D. Shukla, J. Zhang, B. Willis, F. Ampil, A. Nanda. Gamma Knife Radiosurgery in the Management of Brain Metastases from Lung Carcinoma: A Retrospective Analysis of Survival, Local Tumor Control, and Freedom from New Brain Metastases. J Neurosurg 100: 842-847, 2004

I. Kusaka, G. Kusaka, C. Zhou, M. Ishikawa, A. Nanda, D.N. Granger, J. Zhang & J. Tang. Role of AT1 Receptors and NAD(P)H Oxidase in Diabetes-Aggravated Ischemic Brain Injury . Am J Physiol Heart Circ Physiol 286: 2442-2451, 2004 http://dx.doi.org/10.1152/ajpheart.01169.2003

M. Yamaguchi, C. Zhou, A. Nanda, J. Zhang. Ras Protein Contributes to Cerebral Vasospasm in a Canine Double Hemorrhage Model. Stroke 35: 1750-1755, 2004 http://dx.doi.org/10.1161/01.STR.0000129898.68350.9f

G. Kusaka, I. Kusaka, M. Ishikawa, A. Nanda, D.N. Granger, J. Zhang. Signaling Pathways for Early Brain Injury after Subarachnoid Hemorrhage. J Cereb Blood Flow Metab 24: 916-925, 2004 http://dx.doi.org/10.1097/01.WCB.0000125886.48838.7E

M. Ishikawa, D. Cooper, T.V. Arumugam, J. H. Zhang, A. Nanda, D. N. Granger. Platelet-Leukocyte-Endothelial Cell Interactions after Middle Cerebral Artery Occlusion and Reperfusion. J Cereb Blood Flow Metab 24: 907-15, 2004 http://dx.doi.org/10.1097/01.WCB.0000132690.96836.7F

J. Calvert, C. Zhou, J. Zhang. Exposure of Rat Pups to Hyperoxia at Normal and Hyperbaric Pressure does not Cause Retinopathy of Prematurity. Experimental Neurology 189: 150-161, 2004 http://dx.doi.org/10.1016/j.expneurol.2004.05.030

J. Tang, J. Liu, C. Zhou, J.S. Alexander, A. Nanda, D.N. Granger, J.H. Zhang. MMP-9 Deficiency Enhances Collagenase-induced Intracerebral Hemorrhage and Brain Injury in Transgenic Mice. J Cereb Blood Flow Metab 24: 1133-1145, 2004 http://dx.doi.org/10.1097/01.WCB.0000135593.05952.DE

S. Park, M. Yamaguchi, C. Zhou, J. Tang, J. Zhang. Neurovascular Protection Reduces Early Brain Injury after Subarachnoid Hemorrhage. Stroke 35: 2412-2417, 2004 http://dx.doi.org/10.1161/01.STR.0000141162.29864.e9

R. Wang, W. Shi, J. Sun, F. Wang, C. Liu, L. Zhou, B. Bin, J.H. Zhang. Caspase-3 Expression in Neuronal Cells induced by Oxyhemoglobin. Clinical Journal of Experimental Surgery 21: 888, 2004

M. Yamaguchi, C. Zhou, J. Zhang. Gene Transfer of EC-SOD Failed to Prevent Cerebral Vasospasm after Experimental Subarachnoid Hemorrhage. Stroke 35: 2512-2517, 2004 http://dx.doi.org/10.1161/01.STR.0000145198.07723.8e

2004 list

Review

J.H. Zhang. Experimental Therapies for SAH and Cerebral Vasospasm (Review). Chinese Journal of Minimally Invasive Neurosurgery 9 (Suppl): 57-59, 2004

M. Ishikawa, J. Zhang, A. Nanda, D.N. Granger. Inflammatory Responses to Ischemia and Reperfusion in Cerebral Microcirculation (Review). Frontiers in Bioscience 9: 1339-1347, 2004 http://dx.doi.org/10.2741/1330

W. Yin, J. Zhang. Hyperbaric Oxygen Therapy for Cerebral Ischemia (Review). Research SignPost (Recent Res. Devel. Physiol.) 2: 247-257, 2004

Editorial

J.H. Zhang. Introduction to Special Issue: Apoptosis in Cerebral Ischemia. Neurological Research 26: 825-826, 2004

2004 list

Journal Supplement

Y. Dai & J. Zhang. Chloride Efflux Involved in ET-1 and 5-HT Induced Contraction in Rabbit Basilar Artery. J Cardiovasc Pharmacol Supplement 44: Supplement 1: S125-128, 2004 http://dx.doi.org/10.1097/01.fjc.0000166225.96088.bd

A. Zubkov, L. Miao & J. Zhang. Signaling Pathways for ET-1 Induced Contraction in Rabbit Basilar Artery. J Cardiovasc Pharmacol Supplement 44: Supplement 1: S24-26, 2004

Book Chapter

J.H. Zhang. Experimental Therapy for SAH and Cerebral Vasospasm. Advances in Neurosciences-2004. Ed. X. Wang et al. Higher Education Press. Pp 635-645, 2004

H. Kimura, I. Gules, B. Chen, T. Meguro, A. Parent & J. Zhang. Cytokines Produce Apoptosis in Cultured Cerebral Endothelial. Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, R.L. Macdonald. Pp 97-102, 2004

J. Zhang. Signaling Pathways in Cerebral Vasospasm. Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, Ed. R.L. Macdonald. Pp 3-7, 2004

G. Kusaka, H. Kimura, I. Kusaka, E. Perkins, A. Nanda, J. Zhang. Inhibition of Src Tyrosine Kinase reduces Experimental Cerebral Vasospasm. Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, R.L. Macdonald. Pp 17-19, 2004

D. Tyler, V. Overman, E. Flotte, J. Tyler, W. Johnson & J. Zhang. Sex and Racial Factors in the Outcome of Subarachnoid Hemorrhage in Mississippi . Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, R.L. Macdonald. Pp 220-226, 2004

Y. Takanashi, T. Ishida, J.H. Zhang, I. Yamamoto. Prevention of Experimental Cerebral Vasospasm by Intrathecal Delivery of Liposomal Fasudil. Cerebral Vasospasm (8th International Conference on Cerebral Vasospasm) Thieme, R.L. Macdonald. Pp 153-155, 2004

S. Park, C. Zhou, J. Tang, A. Colohan, J.H. Zhang. Apoptosis, Neurovascular Protection, and Subarachnoid Hemorrhage. Pharmacology of Cerebral Ischemia. Ed. J. Krieglstein, S. Klumpp. 2004, p217-227

2004 list

Book Review

J.H. Zhang, Book Review. “The Blood-Brain Barrier: Biology and Research Protocols” S. Nag ed. Totowa, New Jersey: Humana Press INC, 2003. Surgical Neurology 61: 409-410, 2004

J. Zhang. Book Review: Brain Edema XII: Proceedings of the 12th International Symposium. Kakone, Japan, November 10-13, 2002. (Acta Neurochirurgica Supplement 86. T. Kuroiwa, A. Baethmann, Z. Czemicki, J. Hoff, U. Ito, Y. Katayama, A. Marmarou, A.D. Mendelow, and H.J. Reulen, editors. New York: Springer-Verlag/Wein, 2003, 609 pp, illus. ISBN 3-211-00919-1. Price: $259.00.) J Neurosurg 101: 560-562, 2004

Original Article | Review | Editorial Letter | Journal Supplement

Original Article

J. Sung g, L. Miao, J. Calvert, L. Harkey & J. Zhang. Role of RhoA in Spinal Cord Injury. Brain Res 959: 29-38, 2003 http://dx.doi.org/10.1016/S0006-8993(02)03717-4

L. Richards, W.C. Lineaweaver, F. Stile, J. Zhang, F. Zhang. Effect of Hyperbaric Oxygen Therapy on the Tubed Pedicle Flap Survival in a Rat Model. Ann Plast Surg 50: 51-56, 2003 http://dx.doi.org/10.1097/00000637-200301000-00009

E. Perkins, J. Calvert, J. Lancom, A. Parent & J. Zhang. Inhibition of H-ras as a Treatment for Experimental C6 Glioma. Molecular Brain Res 111: 42-51, 2003 http://dx.doi.org/10.1016/S0169-328X(02)00668-X

G. Mandybur, Y. Miyagi, W. Yin, E. Perkins, A. Parent & J. Zhang. Cytotoxicity of Ventricular CSF from Parkinson Patients: Correlation with Clinical Profiles and Neurochemistry. Neurol Res 25: 104-111, 2003 http://dx.doi.org/10.1179/016164103101201021

A. Massey, L. Miao, B. Smith, J. Liu, I. Kusaka, J. Zhang & J. Tang. Increased RhoA Translocation in Renal Cortex of Diabetic Rats. Life Sci 27: 2943-2952, 2003 http://dx.doi.org/10.1016/S0024-3205(03)00228-5

G. Kusaka, H. Kimura, I. Kusaka, E. Perkins, A. Nanda, J. Zhang. Contribution of Src Tyrosine Kinase to Cerebral Vasospasm after Subarachnoid Hemorrhage. J Neurosurg 99: 383-390, 2003

M. Ishikawa, D. Cooper, J. Russell, J.W. Salter, J.H. Zhang, A. Nanda, D.N. Granger. Molecular Determinates of the Prothrombogenic and Inflammatory Phenotype Assumed by the Post Ischemic Cerebral Microcirculation. Stroke 34: 1777-1782, 2003 http://dx.doi.org/10.1161/01.STR.0000074921.17767.F2

D. Yin, C. Zhou, I. Kusaka, J. Calvert, A. Parent, A. Nanda & J. Zhang. Inhibition of Apoptosis by Hyperbaric Oxygen in a Rat Focal Cerebral Ischemic Model. J Cereb Blood Flow Metab 23: 855-864, 2003 http://dx.doi.org/10.1097/01.WCB.0000073946.29308.55

C. Zhou, Y. Li, A. Nanda, J. Zhang. HBO Suppresses Nogo-A, Ng-R, or RhoA Expression in Cerebral Cortex after Global Ischemia. Biochem Biophys Res Comm 309: 368-376, 2003 http://dx.doi.org/10.1016/j.bbrc.2003.08.006

J. Calvert, C. Zhou, A. Nanda, J. Zhang. Effect of HBO on Apoptosis in Neonatal Hypoxia Rat Model. J Applied Physiol 95: 2072-2080, 2003

H. Kimura, I. Gules, T. Meguro & J. Zhang. Cytotoxicity of Cytokines in Cerebral Microvascular Endothelial Cell. Brain Res 990: 148-156, 2003 http://dx.doi.org/10.1016/S0006-8993(03)03450-4

2003 list

Review

J. Zhang, H. Kimura, A. Nanda. New Frontier in Cerebral Vasospasm: Signaling Pathway. Advances in Brain Research - Cerebrovascular Disorders and Neurodegeneration. Excerpta Medica International Congress Series 1251, Neurology, Elsevier Science pp3-15, 2003

A. Zubkov, A. Nanda & J. Zhang. Signal Transduction in Cerebral Vasospasm (Review). Pathophysiology 9: 47-61, 2003 http://dx.doi.org/10.1016/S0928-4680(02)00055-X

Editorial Letter

J. Zhang, A. B. Singhal, J. Toole. Oxygen Therapy in Ischemic Stroke. Letter to the Editor. Stroke 34: E152-153, 2003 http://dx.doi.org/10.1161/01.STR.0000087098.30644.E1

2003 list

Journal Supplement

L. Huang, M. Mehta, A. Nanda & J. Zhang. The Role of Multiple Hyperbaric Oxygenation in Expanding Therapeutic Windows after Acute Spinal Cord Injury in Rats. J Neurosurg 99 (2 Suppl): 198-205, 2003

L. Huang, M. Mehta, J. Eichhorn, A. Nanda & J. Zhang. Multiple Hyperbaric Oxygenation (HBO) Expands the Therapeutic Window in Acute Spinal Cord Injury in Rats. Acta Neurochir Suppl 86: 433-438, 2003

M. Sato, J. Tang, A. Nanda & J. Zhang. Heat Shock Proteins Expression in Brain Stem after Subarachnoid Hemorrhage in Rats. Acta Neurochir Suppl 86: 477-482, 2003

I. Gules, M. Sato, A. Nanda & J. Zhang. Apoptosis, Blood-Brain Barrier, Subarachnoid Hemorrhage. Acta Neurochir Suppl 86: 483-487, 2003

Original Article | Journal Supplement | Book Chapter

Original Article

W. Yin, A. Badr, G. Mychaskiw & J. Zhang. HBO Reduces COX-2 Expression and Infarction in MCAO Rats. Brain Res 926: 165-171, 2002

H. Kimura, K. Sasaki, T. Meguro & J. Zhang. Phosphatidylinositol 3-Kinase Inhibitor Failed to Reduce Cerebral Vasospasm in Dog Model of Experimental Subarachnoid Hemorrhage. Stroke 33: 593-599, 2002 http://dx.doi.org/10.1161/hs0202.103398

M. Sato, A. Parent & J. Zhang. Inhibitory Effect with Antisense Mitogen-activated Protein Kinase Oligodeoxynucleotide against Cerebral Vasospasm in Rats. Stroke 33: 775-781, 2002 http://dx.doi.org/10.1161/hs0302.103734

Y. Dai & J. Zhang. Manipulation of Chloride Flux affects Histamine-induced Contraction in Rabbit Basilar Artery. Am J Physiol Heart Circ Physiol 282: H1427-36, 2002

E. Akin, B. Clower, R. Tibbs, J. Tang & J. Zhang. Bilirubin Induces Apoptosis in Cultured Brain Endothelial Cells. Brain Res 931: 168-175, 2002 http://dx.doi.org/10.1016/S0006-8993(02)02276-X

K. Aoki, A. Zubkov, R. Tibbs & J. Zhang. Role of MAPK in Chronic Cerebral Vasospasm. Life Sci 70: 1901-1908, 2002 http://dx.doi.org/10.1016/S0024-3205(02)01499-6

A. Zubkov, S. Rollins & J. Zhang. KCl-induced MAPK Activation and Contraction in Rabbit Basilar Artery. Biochem Biophys Res Commun 293: 660-664, 2002

AY. Zubkov, R. Tibbs, B. Clower, K. Ogihara, K. Aoki & J.H. Zhang. Morphological Changes of Cerebral Arteries in a Canine Double Hemorrhage Model. Neurosci Lett 326: 137-141, 2002 http://dx.doi.org/10.1016/S0304-3940(02)00188-X

H. Kimura, T. Meguro, A. Badr & J. Zhang. Suramin-induced Reversal of Chronic Cerebral Vasospasm in Experimental Subarachnoid Hemorrhage. J Neurosurg 97: 129-135, 2002

M. Sato, E. Perkins, H. Kimura, C. Yi, D. Heistat, J. Tang & J. Zhang. Post-treatment with Adenovirus-mediated Gene Transfer of Calcitonin Gene-related Peptide to Reverse Cerebral Vasospasm in Dogs. J Neurosurg 97: 136-142, 2002

A. Zubkov, K. Aoki, A. D. Parent & J. Zhang. Preliminary Study of the Effect of Caspase Inhibitors on Vasospasm in Dog Penetrating Arteries. Life Sci 70: 3007-3018, 2002 http://dx.doi.org/10.1016/S0024-3205(02)01550-3

L. Miao, J. Calvert, J. Tang & J. Zhang. Up-regulation of Small GTPase RhoA in the Basilar Artery from Diabetic (mellitus) Rat. Life Sci 71: 1175-1185, 2002 http://dx.doi.org/10.1016/S0024-3205(02)01827-1

S. Rollins, E. Perkins, G. Mandybur & J. Zhang. OxyHb Prevents Growth of Astrocytes. Brain Res 945: 41-49, 2002

L. Miao, Y. Dai & J. Zhang. Mechanisms of RhoA/ROK kinase Activation in Endothelin-1-induced Contraction in Rabbit Basilar Artery. Am J Physiol Heart Circ Physiol 283(3):H983-9, 2002

W. Yin, R. Tibbs, J. Tang, A. Badr & J. Zhang. Role of Hemoglobin and ATP in Cerebral Vasosapsm. J Clin Neurosci 9:425-428, 2002

J.W. Calvert, W. Yin, M. Patel, A. Badr, G. Mychaskiw, A. Parent & J. Zhang. Hyperbaric Oxygenation Prevented Brain Injury induced by Hypoxia-Ischemia in a Neonatal Rat Model. Brain Res 951: 1-8, 2002 http://dx.doi.org/10.1016/S0006-8993(02)03094-9

E. Perkins, H. Kimura, A. Parent & J. Zhang. Evaluation of the Micro-vasculature and Cerebral Ischemia after Experimental Subarachnoid Hemorrhage in Dogs. J Neurosurg 97: 896-904, 2002

I. Gules, M. Sato, B. Clower, A. Nanda & J. Zhang. Comparison of Three Rat Models of Cerebral Vasospasm. Am J Physiol Heart & Circ Physiol 283: H2551-2559, 2002

K. Aoki, A. Zubkov, I. Ross & J. Zhang. Therapeutic Effect of Caspase Inhibitors in the Prevention of Apoptosis and Reversal of Chronic Cerebral Vasospasm. J Clin Neurosci 9: 672-677, 2002 http://dx.doi.org/10.1054/jocn.2002.1088

2002 list

Journal Supplement

Yin W, Tibbs R, Aoki K, Badr A, Zhang J. Metabolic Alterations in Cerebrospinal Fluid from Double Hemorrhage Model of Dogs. Acta Neurochir Suppl 81:257-63, 2002

Book Chapter

J. Zhang, M. Satoh, D. Heistad, A. Nanda. Signal Transduction and Gene Therapy for Cerebral Vasospasm. Pharmacology of Cerebral Ischemia. Ed. J. Krieglstein, S. Klumpp. Pp 141-150, 2002

Original Article | Review | Editorial | Journal Supplement | Book Chapter

Original Article

A. Zubkov, S. Rollins, A. Parent & J. Zhang. Relaxant Effect of U0126 in Hemolysate-, Oxyhemoglobin- and Bloody Cerebrospinal fluid-induced Contraction in Rabbit Basilar Artery. Stroke 32: 154-161, 2001

T. Meguro, B. Chen, A. Parent & J. Zhang. Caspase II and III Inhibitors Prevent Oxyhemoglobin-induced Apoptotic Changes in Endothelial Cells. Stroke 32: 561-566, 2001

W. Yin, R. Tibbs, A. Badr & J. Zhang. Metabolic Alterations in CSF from Double Hemorrhage Model of Dogs. Neurol Res 23: 87-92, 2001 http://dx.doi.org/10.1179/016164101101198181

R. Carpenter, L. Miao, Y, Miyagi, E. Bengten & J. Zhang. Altered Expression of P(2) Receptor mRNAs in the Basilar Artery in a Rat Double Hemorrhage Model. Stroke 32: 516-522, 2001

A. Badr, W. Yin, G. Mychaskiw & J. Zhang. Dual Effect of Hyperbaric Oxygen on Cerebral Infarction in Rat MCA Occlusion Model. Am J Physiol Regul Integr Comp Physiol 280: R766-R770, 2001

K. Ogihara, K. Aoki, A. Zubkov & J. Zhang. Oxyhemoglobin Produces Apoptosis and Necrosis in Cultured Smooth Muscle Cells. Brain Res 889 (1-2): 89-97, 2001 http://dx.doi.org/10.1016/S0006-8993(00)03120-6

T. Meguro, B. Chen, J. Lancon & J. Zhang. OxyHb Induces Caspase-mediated Cell Death in Cerebral Endothelial Cells. J Neurochem 77: 1128-1135, 2001 http://dx.doi.org/10.1046/j.1471-4159.2001.00313.x

Y. Takanashi, T. Ishida, T. Meguro, H. Kiwada, J. Zhang & I. Yamamoto. Efficacy of Intrathecal Liposome Fasudil for Experimental Cerebral Vasospasm following Subarachnoid Hemorrhage in Dogs. Neurosurgery 48: 894-901, 2001 http://dx.doi.org/10.1097/00006123-200104000-00041

K. Aoki. R. Williams & J. Zhang. Mechanism of Hemolysate-induced [Ca 2+]i Elevation in Cultured Human Fibroblasts. Neurol Res 23: 367-373, 2001 http://dx.doi.org/10.1179/016164101101198578

T. Meguro, B. Clower, R. Carpenter, A. Parent & J. Zhang. Improved Rat Model in Cerebral Vasospasm Studies. Neurol Res 23: 761-766, 2001 http://dx.doi.org/10.1179/016164101101199144

L. Miao, J. Calvert, J. Tang, A. Parent & J. Zhang. Age-related Rho -A Expression in Blood Vessels of Rats. Mech Aging Dev 122: 1757-1770, 2001 http://dx.doi.org/10.1016/S0047-6374(01)00297-4

A. Badr, W. Yin, G. Mychaskiw & J. Zhang. Effect of Hyperbaric Oxygen on Striatal Metabolites: A Micro-dialysis Study in Awaken Freely Moving Rats after MCA Occlusion. Brain Res 916: 85-90, 2001 http://dx.doi.org/10.1016/S0006-8993(01)02867-0

Y. Dai, J. Zhang. Role of Chloride Channels in Endothelin-1 Induced Contraction in Rabbit Basilar Artery. Am J Physiol Heart Circ Physiol 281: H2159-2167, 2001

Y. Takanashi, T. Ishida, T. Meguro, M.J. Kirchmeier, T.M. Allen, J.H. Zhang. Intrathecal Application with Liposome-entrapped Fasudil for Cerebral Vasospasm following Subarachnoid Hemorrhage in Rats. J Clin Neuroscience 8: 557-561, 2001 http://dx.doi.org/10.1054/jocn.2001.0998

L. Miao, J. Tang, D. Esposito & J. Zhang. Age-related Changes of P 2 Receptor mRNAs of Rat Cerebral Arteries. Experimental Gerontology 37: 67-79, 2001 http://dx.doi.org/10.1016/S0531-5565(01)00159-0

2001 list

Review

I. Laher & J. Zhang. Protein Kinase C and Cerebral Vasospasm (Review). J Cereb Blood Flow Metab 21: 887-906, 2001 http://dx.doi.org/10.1097/00004647-200108000-00001 

J. Zhang. The Role of MAPK in Cerebral Vasospasm (Review). Drug News & Perspectives 14(5): 261-267, 2001 http://dx.doi.org/10.1358/dnp.2001.14.5.858392

Editorial

J. Zhang. Editorial: A New Era in Stroke Research. Journal of Stroke 1: 4, 2001

2001 list

Journal Supplement

Y. Takanashi, T. Ishida, T. Meguro, M. Kirchmeier, T. Allen, J. Zhang. A Novel Drug Delivery System as Prophylaxis for Cerebral Vasospasm. Acta Neurochirugica (Suppl) 77 (44): 213-216, 2001

K. Aoki, A. Zubkov, R. Tibbs, T. Meguro, J. Zhang. Role of MAPK in Chronic Cerebral Vasospasm. Acta Neurochirugica (Suppl) 77 (44): 55-58, 2001

A. Zubkov, K. Rollins, B. McGehee, A. Parent, J. Zhang. Role of Mitogen-activated Protein Kinase in the Contractions of Rabbit Basilar Artery induced by Hemolysate, Oxyhemoglobin, and Bloody CSF. Acta Neurochirugica (Suppl) 77 (44): 25-28, 2001

A. Zubkov, R. Tibbs, B. Clower, K. Ogihara, K. Aoki, J. Zhang. Apoptosis in Basilar Endothelial Cells in a Canine Double Hemorrhage Model. Acta Neurochirugica (Suppl) 77 (44): 29-32, 2001

2001 list

Book Chapter

H. Kimura, R. Carpenter, A. Parent, J. Zhang. Role of ATP/P2 Receptors in Cerebral Vasospasm. Proceedings of the 7th World congress for Microcirculation. Sidney, Australia, August 19-23, 2001

Editor for Special Journal Issue | Original Article | Review | Editorial Letter | Journal Supplement | Book Chapter

Editor for Special Journal Issue

J.H. Zhang: On-line Proceedings of Stroke/Cerebral Vascular Physiology Symposium of the 6th Internet World Congress on Biomedical Sciences 2000 at Hospital of Ciudad Real, Ciudad Real, Spain

Original Article

A. Zubkov, S. Rollines, A. Parent & J. Zhang. Mechanism of Endothelin-1 Induced Contraction in Rabbit Basilar Artery. Stroke 31: 526-533, 2000

K. Aoki, A. Parent & J. Zhang. Damnacanthal Releases Ca 2+ from Internal Stores and Promotes Ca 2+ Entry in Rat Basilar Smooth Muscle Cells. Eur J Pharmacol 387: 119-124, 2000

A. Zubkov, A. Lewis, F. Raila, J. Zhang & A. Parent. Risk Factors for the Development of Post-traumatic Vasospasm. Surg Neurol 53: 126-130, 2000

K. Ogihara, A.Y. Zubkov, D.H. Bernanke, A.D. Parent & J. Zhang. The Effects of Endothelin Receptor Antagonists on Non-Muscle Matrix Compaction in a Cell Culture Vasospasm Model. Neurol Res 22: 209-214, 2000

A.Y. Zubkov, K. Ogihara, A. Parent & J. Zhang. Apoptosis of Endothelial Cells in Vessel Affected by Cerebral Vasospasm. Surgical Neurol 53: 260-266, 2000

A. Patlolla, A. Zubkov, A. Parent & J. Zhang. Hemolysate Activate p21Ras in Rabbit Basilar Artery. Life Sci 67: 1233-1242, 2000

K. Aoki. A. Zubkov, A. Parent & J. Zhang. Mechanism of ATP-Induced [Ca 2+ ] i mobilization in Rat Basilar Smooth Muscle Cells. Stroke 31: 1377-1385, 2000

Y. Miyagi, R. Carpenter, T. Meguro, A. Parent & J. Zhang. Up-regulation of Rho -A and Rho-kinases in Rat Double Hemorrhage Model. J Neurosurg 93: 471-476, 2000

T. Meguro, C. Klett, B. Chen, A. Parent, & J. Zhang. Role of Ca 2+ Channels in Oxyhemoglobin-induced Apoptosis in Endothelial Cells. J Neurosurg 93: 650-656, 2000

G. Mychaskiw, A. Badr, R. Tibbs, B. Clower & J. Zhang. Optison (FS069) Disrupts the Blood-Brain Barrier in Rats. Anesthesia and Analgesia 91: 798-803, 2000

R. Tibbs, A. Zubkov, K. Aoki, T. Meguro, A. Badr, A. Parent & J. Zhang. Effects of Mitogen-activated Protein Kinase Inhibitors on Cerebral Vasospasm in a Double-Hemorrhage Model in Dogs. J Neurosurg 93: 1041-1047, 2000

A. Zubkov, R. Tibbis, K. Aoki & J. Zhang. Morphological Changes in Cerebral Penetrating Arteries in a Canine Double Hemorrhage Model. Surg Neurol 54: 212-220, 2000

A. Zubkov, R. Tibbs, K. Aoki & J. Zhang. Prevention of Vasospasm in Penetrating Arteries with MAPK Inhibitors in a Dog Double-Hemorrhage Model. Surg Neurol 54: 221-228, 2000

J. Tang & J. Zhang. Mechanism of Ca 2+ Elevation by H 2 O 2 in Islets of Rats. Life Sci 68: 475-481, 2000

2000 list

Review

J. Zhang. Protein Kinase C and Cerebral Vasospasm: Past and Future (Review). Neurol Res 22: 369-378, 2000

Editorial Letter

J. Zhang. Oxyhemoglobin and Apoptosis. Letter to the Editor. J Neurosurg 92: 899-902, 2000

J. Zhang. Oxyhemoglobin and Intracellular Calcium. Letter to the Editor. J Neurosurg 93: 370-371, 2000

2000 list

Journal Supplement

K. Ogihara, A. Zubkov, A. Parent & J. Zhang. Oxyhemoglobin Produces Necrosis in Cultured Smooth Muscle Cells. Acta Neurochirurgica (suppl) 76: 507-510, 2000

A. Patlolla, K. Ogihara, A. Zubkov, K. Aoki, A. Parent & J. Zhang. Role of Tyrosine Kinase in Fibroblast Compaction and Cerebral Vasospasm. Acta Neurochirurgica (suppl) 76: 227-230, 2000

A.Y. Zubkov, A. Pilkington, A.D. Parent & J.H. Zhang. Morphological Presentation of Post-traumatic Vasospasm. Acta Neurochirurgica (suppl) 76: 223-226, 2000

A. Zubkov, K. Ogihara, A. Patlolla, A. Parent & J. Zhang. Mitogen-activated Protein Kinase Plays an Important Role in Hemolysate-induced Contraction in Rabbit Basilar Artery. Acta Neurochirurgica (suppl) 76: 217-221, 2000

2000 list

Book Chapter

K. Ogihara, A. Zubkov, R. Tibbs, A. Parent & J. Zhang. Role of Apoptosis in Cerebral Vasospasm after Subarachnoid Hemorrhage. Ed Y. Fukuuchi, M. Tomita. Ischemic Blood Flow in the Brain. Springer, 2000, pp 202-208

J. Zhang. Protein Kinase C Net Work in Cerebral Vasospasm. Ed. M. Garcia-Rojo. On-line Proceedings of the 6 th Internet World Congress on Biomedical Sciences'2000 at Hospital of Ciudad Real, Ciudad Real, Spain .

R. Tibbs, J. Tang & J. Zhang. Bilirubin Produces Apoptosis in Cultured Endothelial Cells. Ed. M. Garcia-Rojo. On-line Proceedings of the 6 th Internet World Congress on Biomedical Sciences'2000 at Hospital of Ciudad Real, Ciudad Real, Spain .

A. Zubkov, R. Tibbs & J. Zhang. Morphological Changes in Cerebral Penetrating Arteries during Vasospasm. Ed. M. Garcia-Rojo. On-line Proceedings of the 6 th Internet World Congress on Biomedical Sciences'2000 at Hospital of Ciudad Real, Ciudad Real, Spain

T. Meguro, C. Klett & J. Zhang. Role of Calcium Channels in OxyHb-induced Apoptosis in Endothelial Cells. Ed. M. Garcia-Rojo. On-line Proceedings of the 6th Internet World Congress on Biomedical Sciences'2000 at Hospital of Ciudad Real, Ciudad Real, Spain

J. Zhang. Stroke/Cerebral Vascular Physiology. Conference Proceedings of the 6 th Internet World Congress for Biomedical Sciences. Ed. M. Garcia-Rojo. June 2000. Pp12-13

A. Zubkov & J. Zhang. Cerebral Vasospasm of Penetrating Arteries in Brain Stem. Pharmacology of Cerebral Ischemia. Ed. J. Krieglstein, S. Klumpp. 2000, Pp307-316

Original Article

R.L. MacDonald, J. Zhang, L. Marton & B. Weir. Effects of Cell-permeant Calcium Chelators on Contractility in Monkey Basilar Artery. J Neurotrauma 16: 37-47, 1999

J.R. Brorson, P.T. Schumacker & H. Zhang. Nitric Oxide Acutely Inhibits Neuronal Energy Production. J Neuroscience 19: 147-158, 1999

S. Iwabuchi, L.S. Marton & J. Zhang. Tyrosine Kinase Mediated The Effect of Hemolysate on [Ca2+]i in Rat Basilar Smooth Muscle Cells. J Neurosurg 90: 127-135, 1999

A. Zubkov, K. Ogihara, P. Tumu, A. Patlolla, A. Lewis, A. Parent & J. Zhang. Mitogen-activated Protein Kinase Mediates Hemolysate-induced Contraction of Rabbit Basilar Artery. J Neurosurg 90: 1091-1097, 1999

A.Y. Zubkov, K. Ogihara, P. Tumu, G. Mandybur, A. Lewis, A. Parent & J. Zhang. Bloody Cerebrospinal Fluid Alters Contractility of Cultured Arteries. Neurol Res 21: 553-558, 1999

C.J. Kim, K.W. Kim & J. Zhang. Role of KCa in Hemolysate-induced Contraction of Rabbit Basilar Artery. Neurol Res 21: 705-711, 1999

K. Ogihara, A. Zubkov, D.H. Bernanke, A. Lewis, A. Parent & J. Zhang. Oxyhemoglobin Produced Apoptosis in Cultured Endothelial Cells. J Neurosurg 91: 459-465, 1999

A. Zubkov, A.S. Pilkington, D. Bernanke, A.D. Parent & J. Zhang & A. Parent. Post-traumatic Cerebral Vasospasm: Clinical and Morphological Presentations. J Neurotrauma 16: 763-770, 1999

A. Patlolla, K. Ogihara, K. Aoki, A. Zubkov, E. Bengten, A. Parent & J. Zhang. Hemolysate Induced Tyrosine Phosphorylation and Collagen-Lattice Compaction in Cultured Fibroblasts. Biochem Biophys Res Comm 264: 100-107, 1999

Editorial

M. Boegehold, R.M.K.W. Lee, M.J. Mulvany, B. Nilius, R.L. Prewitt & J. Zhang. Vascular Research at INABIS 98. J Vasc Res (Blood Vessels) 36: 147-150, 1999

Book Chapter

B. Sima, B. Weir, RL. Macdonald & H. Zhang. P2u Receptors Mediated The Effect of Hemolysate on [Ca2+]I in Rat Basilar Smooth Muscle Cells. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 40-42, 1999

C.J. Kim, K.W. Kim, J.W. Park, J.C. Lee & H. Zhang. Role of Tyrosine Phosphorylation in Hemolysate-induced Contraction in Rabbit Basilar Artery. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 43-44, 1999

C.J. Kim, J.C. Lee & H. Zhang. Hemolysate Modulates Cerebral Vascular Smooth Muscle Potassium and Calcium Channels. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 31-32,1999

R.L. Macdonald, J. Zhang & A. Hino. Characterization of Endothelin Receptors in Monkey Basilar Artery. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 2-6, 1999

R.L. Macdonald, B. Weir, J. Zhang, L. Marton, M Sajdak & L. Johns. Adenosine Triphosphate as A Possible Cause of Vasospasm In Monkeys. Ed N.W.C. Dorsch. Cerebral Vasospasm VI. Oslington Consulting Pty Ltd. 58-62, 1999

Editor for Special Journal Issue

J.H. Zhang: On-line Proceedings of Stroke/Cerebral Vasospasm Symposium of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada, 1998

Original Article

C.J. Kim, B. Weir, R.L. Macdonald & H. Zhang. Hemolysate Releases Ca2+ from IP3 Receptors and Activates Ca2+-Dependent K+ Channels in Rat Basilar Smooth Muscle Cells. Neurol Res 20: 23-30, 1998

R.L. Macdonald, J. Zhang, B. Weir, L. Marton & R. Wollman. Adenosine Triphosphate Causes Vasospasm of the Rat Femoral Artery. Neurosurgery 42: 825-833, 1998

C.J. Kim, K.W. Kim, J.W. Park, J.C. Lee & J. Zhang. Role of Tyrosine Kinase in Erythrocyte Lysate-induced Contraction of Rabbit Cerebral Arteries. J Neurosurg 89: 289-296, 1998

Y. Guan, B. Weir, L.S. Marton, R.L. Macdonald & H. Zhang. Comparison of the Effects of Hemolysate at Different Ages on [Ca2+]i in Rat Basilar Arterial Cells. J Neurosurg 89: 1007-1014, 1998

Review

H. Zhang, A. Lewis, D. Bernanke, A. Zubkov & B. Clower. Stroke - Anatomy of A Catastrophic Event (Review). Anat Rec (New Anat) 253: 58-63, 1998

Book Chapter

H. Zhang, B. Sima, RL Macdonald & B. Weir. P2 Receptors in Cerebral Arteries. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

J. Zhang, K. Ogihara, D. Bernanke, A. Lewis & A. Parent. Oxyhemoglobin Produced Apoptosis in Cultured Endothelial. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

A.Y. Zubkov, K. Ogihara, P. Tumu, A.I. Lewis, A.D. Parent, J. Zhang. Mitogen-activated Protein Kinase is involved In the Pathogenesis of Cerebral Vasospasm. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

S. Iwabuchi, J. Zhang, L. Marton etc. Tyrosine Kinase and Cerebral Vasospasm. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

R.L. Macdonald, J. Zhang, L. Marton, B. Weir etc. Spasmogens in Cerebral Vasospasm. Ed H. Szechtman. On-line Proceedings of the 5th Internet World Congress on Biomedical Sciences'98 at McMaster University, Canada.

Original Article

J. Brorson, R.A. Sulit & H. Zhang. Nitric Oxide Disrupts Ca2+ Homeostasis in Hippocampal Neurons. J Neurochem 68: 95-105, 1997

J. Kane, R.L. Macdanold, J. Zhang & B. Sima. HEPES Inhibits Contractile Responses of Canine Basilar Artery. Neurol Res 19: 527-533, 1997

H. Zhang, B. Weir, L. Marton, K. Lee & L. Macdonald. P2 Purinoceptors in Bovine Middle Cerebral Artery Endothelial Cells. J Cardiovsc Pharmacol 30: 767-774, 1997

B. Sima, B. Weir, R.L. Macdonald & H. Zhang. Extracellular Nucleotide-Induced [Ca2+]i Elevation in Rat Basilar Smooth Muscle Cells. Stroke 28: 2053-2059, 1997

J. Brorson & H. Zhang. Disrupted [Ca2+]i Homeostasis Contributes to the Toxicity of Nitric Oxide in Cultured Hippocampal Neurons. J Neurochem 69: 1882-1889, 1997

R.L. Macdonald, B. Weir, J. Zhang, L.S. Marton, M. Sajdak, L.M. Johns. Adenosine Triphosphate and Hemoglobin in Vasospastic Monkeys. J Neurosurg (Neurosurg Focus) 3: article 3, 1-7, 1997

Original Article

J. Tang, W. Pugh, K. Polonsky & H. Zhang. Preservation of Insulin Secretary Responses to P2-Purinoceptor Agonists in Zucker Diabetic Fatty Rats. Am J Physiol Endocri Physiol 270: E504-512, 1996

C.J. Kim, B. Weir, R.L. Macdonald, L.S. Marton & H. Zhang. Hemolysate Inhibits L-Type Ca2+ Channels in Rat Basilar Smooth Muscle Cells. J Vascular Res (Blood Vessels) 33: 258-264, 1996

H. Zhang, B. Sima, L.M. Johns & R.L. Macdonald. Time Course of Changes in Arterial Relaxation Following Subarachnoid Hemorrhage in Dogs. Neurol Res 18: 227-232, 1996

H. Zhang, B. Weir, R.L. Macdonald & L. Marton. Mechanisms of [Ca2+]i Elevation Induced by Erythrocyte Components in Endothelial Cells. J Pharmacol Exp Ther 277: 1501-1509, 1996

L.S. Marton, B. Weir & H. Zhang. Tyrosine Phosphorylation And [Ca2+]i Elevation Induced by Hemolysate in Bovine Endothelial Cells: Implication for Cerebral Vasospasm. Neurol Res 18: 349-353, 1996

B. Sima, R.L. Macdanold, B. Weir, L. Marton & H. Zhang. Effect of P2-Purinoceptor Antagonists on Hemolysate- and ATP-Induced Contractions of Dog Basilar Artery in Vitro. Neurosurgery 39: 815-822, 1996

Book Chapter

R.L. Macdonald, X. Wang, J. Zhang & L. Marton. Molecular Changes with Subarachnoid Hemorrhage and Vasospasm. Ed. C. Raffel, G. Harsh. The Molecular Biology of Neurosurgical Disease. Concepts in Neurosurgery, Vol. 8. Williams & Wilkins, Baltimore, 1996, chapter 17, pp278-293

Original Article

M. Inazu, H. Zhang & E. Daniel. Different Mechanisms Can Activate Ca2+ Entrance via Cation Currents In Endothelial Cells. Life Sci 56: 11-17, 1995

H. Zhang, B. Weir & E. Daniel. Activation of Protein Kinase C Inhibits Potassium Currents. Pharmacology 50: 247-256, 1995

R.L. Macdonald, J. Zhang & H. Han. Pharmacological Study of Effect of Angioplasty on Rabbit Carotid Arteries with and Without Vasospasm. Stroke 26: 1053-1059, 1995

R.L. Macdonald, J. Zhang, B. Sima & L. Johns. Papaverine-sensitive Vasospasm and Arterial Contractility and Compliance Following Subarachnoid Hemorrhage in Dogs. Neurosurgery 37: 962-968, 1995

H. Zhang, B. Weir, L. Marton, R.L. Macdonald, V. Bindokas, R. Miller & J. Brorson. Mechanisms of Hemolysate-induced Calcium Elevation in Cerebral Smooth Muscle Cells. Am J Physiol Heart Circulatory Physiol 269: H1874-1890, 1995

Original Article

H. Zhang, M. Inazu, B. Weir, M. Buchanan & E. Daniel. Cyclopiazonic Acid Stimulates Calcium Influx through Non-Specific Cation Channels In Endothelial Cells. Eur J Pharmacol 251: 119-125, 1994

H. Zhang, M. Inazu, B. Weir & E. Daniel. Endothelin-1 Inhibits Inward Rectifier Potassium Channel and Activates Non-Specific Cation Channel in Cultured Endothelial Cells. Pharmacology 49: 11-22, 1994

M. Inazu, H. Zhang & E. Daniel. Properties of the LP-805-induced Potassium Currents in Cultured Bovine Pulmonary Endothelial Cells. J Pharmacol Exp Ther 268: 403-408, 1994

H. Zhang & D. Cook. Antagonism of Eicosanoid-induced Contraction of Rat Aorta by Sulphonylureas. Pharmacology 49: 173-183, 1994

Review

H. Zhang & D. Cook. Cerebral Vascular Smooth Muscle Potassium Channels and Their Possible Role in the Management of Cerebral Vasospasm (Review). Pharmacol & Toxicol 75: 327-336, 1994

Original Article

M. Inazu, H. Zhang & E. Daniel. LP-805, A Releaser of Endothelium-derived Nitric Oxide, Activates an Endothelial Calcium Permeable Non-Specific Cation Channel. Life Sci 53: PL 315-320, 1993

Y. Guan, J. Zhang, R. Lee, C. Kwan & E. Daniel. Cyclopiazonic Acid Enhanced the Ca2+-Dependent Outward K+ Currents in Cultural Aortic Smooth Muscle Cells from SHR and WKY. Chinese Pharmacol Bull 9: 257-260, 1993

Book Chapter

H. Zhang, M. Inazu, E. Daniel & B. Weir. Cyclopiazonic Acid Releases Nitric Oxide from Endothelium by Stimulate Calcium Influx through Non-selective Cation Channels. Ed. J.M. Findlay. Developments in Neurology 8: Cerebral Vasospasm. Elsevier Science Publisher B.V. 225-228, 1993

H. Zhang, M. Inazu, E. Daniel & B. Weir. Activation of Protein Kinase C Inhibits Potassium Channels in Cultured Endothelial Cells. Ed. J.M. Findlay. Developments in Neurology 8: Cerebral Vasospasm. Elsevier Science Publisher B.V. 133-136, 1993

M. Inazu, H. Zhang, E. Daniel & B. Weir. Effects of LP-805, A Releaser of Endothelium-derived Nitric Oxide, On Ion Channels in Cultured Endothelial Cells. Ed.J.M. Findlay. Developments in Neurology 8: Cerebral Vasospasm. Elsevier Science Publisher B.V. 243-246, 1993

Original Article

H. Zhang, B. Weir, N. Stockbridge, M. Doi & D. Cook. Glibenclamide Inhibits the Contractile Responses of Canine Middle Cerebral Artery To Eicosanoids And Oxyhemoglobin. Cerebrovasc Dis 2: 51-57, 1992

H. Zhang, N. Stockbridge, B. Weir, B. Vollrath & D. Cook. Vasodilatation of Canine Cerebral Arteries by Nicorandil, Pinacidil and Lemakalim. Gen Pharmacol 23: 197-201, 1992

N. Stockbridge, H. Zhang & B. Weir. Potassium Currents of Rat Basilar Artery Smooth Muscle Cells. Pflügers Arch 420: 37-42, 1992

H. Zhang, B. Weir, M. Doi, H. Kasuya & D. Cook. Relaxant Effects of Iloprost in Canine Cerebral Artery. Can J Physiol Pharmacol 70: 712-716, 1992

Original Article

H. Zhang, N. Stockbridge, B. Weir, C. Krueger & D. Cook. Glibenclamide Relaxes Vascular Smooth Muscle Constriction Produced by Prostaglandin F2a. Eur J Pharmacol 195: 27-35, 1991

N. Stockbridge, H. Zhang & B. Weir. Effects of K+ Channel Agonists Cromakalim and Pinacidil On Rat Basilar Artery Smooth Muscle Cells Are Mediated By Ca++-Activated K+ Channels. Biochem Biophys Res Commun 181: 172-178, 1991

Book Chapter

H. Zhang, N. Stockbridge & B. Weir. Effects of Pinacidil, Cromakalim and Nicorandil on Potassium Currents of Rat Basilar Artery Smooth Muscle. Adv Exp Med Biol 304: 531-541, 1991